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原发性肾脏活检后的并发症:明确的数据。

Complications after native kidney biopsy: definitive data.

机构信息

Néphrologie-Hypertension, Dialyses, Transplantation rénale, Hôpital Bretonneau, CHU Tours.

EA4245, University of Tours, Tours.

出版信息

Curr Opin Nephrol Hypertens. 2021 Nov 1;30(6):555-558. doi: 10.1097/MNH.0000000000000736.

DOI:10.1097/MNH.0000000000000736
PMID:34412087
Abstract

PURPOSE OF REVIEW

To assess the risk of complications associated with native kidney biopsies. This review will highlight recent advances on the risk factors for major bleeding and risk management in patients with native kidney biopsy.

RECENT FINDINGS

Recent studies provided new important data regarding the individualization of the risk of bleeding after kidney biopsy. A new bleeding risk score was proposed as a risk stratification tool, useful for shared decision making and procedure choice.

SUMMARY

The risk of complications is low (<1%) in most patients but varies widely. Risk factors include Charlson index, frailty index, female gender, dyslipidemia, anemia, thrombocytopenia, cancer, abnormal kidney function, glomerular disease, autoimmune disease, vasculitis, hematologic disease, and thrombotic microangiopathy. A new bleeding score can help physicians and patients to assess the risk of bleeding enabling informed consent, and decide to perform it or not, and to prefer transjugular vs percutaneous route.

摘要

目的综述

评估与肾活检相关的并发症风险。本文将重点介绍肾活检患者发生大出血的风险因素及风险管理的最新进展。

最近的发现

最近的研究提供了有关肾活检后出血风险个体化的新重要数据。提出了一种新的出血风险评分作为风险分层工具,有助于共同决策和选择操作。

总结

大多数患者并发症的风险较低(<1%),但差异很大。危险因素包括Charlson 指数、衰弱指数、女性、血脂异常、贫血、血小板减少症、癌症、肾功能异常、肾小球疾病、自身免疫性疾病、血管炎、血液病和血栓性微血管病。新的出血评分可以帮助医生和患者评估出血风险,从而进行知情同意,并决定是否进行肾活检,以及选择经颈静脉入路还是经皮入路。

相似文献

1
Complications after native kidney biopsy: definitive data.原发性肾脏活检后的并发症:明确的数据。
Curr Opin Nephrol Hypertens. 2021 Nov 1;30(6):555-558. doi: 10.1097/MNH.0000000000000736.
2
Major Bleeding and Risk of Death after Percutaneous Native Kidney Biopsies: A French Nationwide Cohort Study.经皮肾穿刺活检后主要出血和死亡风险:一项法国全国队列研究。
Clin J Am Soc Nephrol. 2020 Nov 6;15(11):1587-1594. doi: 10.2215/CJN.14721219. Epub 2020 Oct 15.
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Risk factors associated with significant bleeding events after ultrasound-guided percutaneous native renal biopsies: a review of 2204 cases.超声引导下经皮肾活检后发生严重出血事件的相关风险因素:2204 例病例回顾。
Abdom Radiol (NY). 2019 Jun;44(6):2316-2322. doi: 10.1007/s00261-019-01962-z.
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Safety of Kidney Biopsy when Performed as an Outpatient Procedure.经门诊施行肾脏切片检查之安全性。
Kidney Blood Press Res. 2021;46(3):310-322. doi: 10.1159/000515439. Epub 2021 Jun 2.
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Risk Factors for Severe Bleeding Complications in Percutaneous Renal Biopsy.经皮肾活检严重出血并发症的危险因素
Am J Med Sci. 2017 Mar;353(3):230-235. doi: 10.1016/j.amjms.2016.12.019. Epub 2016 Dec 31.
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Major Bleeding of Transjugular Native Kidney Biopsies. A French Nationwide Cohort Study.经颈静脉进行的自体肾活检的大出血:一项法国全国性队列研究。
Kidney Int Rep. 2021 Jul 17;6(10):2594-2603. doi: 10.1016/j.ekir.2021.07.011. eCollection 2021 Oct.
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Utility of transjugular renal biopsy as an alternative to percutaneous biopsy.经颈静脉肾活检作为经皮肾活检的替代方法的效用。
Nefrologia (Engl Ed). 2020 Nov-Dec;40(6):634-639. doi: 10.1016/j.nefro.2020.04.018. Epub 2020 Jul 11.
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Acute Kidney Disease Increases the Risk of Post-Kidney Biopsy Bleeding Complications.急性肾脏病增加肾活检后出血并发症的风险。
Kidney Blood Press Res. 2020;45(6):873-882. doi: 10.1159/000509443. Epub 2020 Oct 26.
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A Universal Bleeding Risk Score in Native and Allograft Kidney Biopsies: A French Nationwide Cohort Study.自体肾活检和同种异体肾活检的通用出血风险评分:一项法国全国队列研究。
J Clin Med. 2023 May 17;12(10):3527. doi: 10.3390/jcm12103527.
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Thromboelastography versus bleeding time for risk of bleeding post native kidney biopsy.血栓弹力描记术与出血时间用于预测原发性肾脏活检后出血风险。
Ren Fail. 2020 Nov;42(1):10-18. doi: 10.1080/0886022X.2019.1700805.

引用本文的文献

1
Image-guided renal parenchymal biopsies- how we do it.图像引导下的肾实质活检——我们的操作方法。
Abdom Radiol (NY). 2025 Jun;50(6):2595-2605. doi: 10.1007/s00261-024-04690-1. Epub 2024 Nov 25.
2
Thrombotic microangiopathies after kidney transplantation in modern era: nosology based on chronology.现代时代肾移植后的血栓性微血管病:基于时间顺序的分类学。
BMC Nephrol. 2023 Sep 20;24(1):278. doi: 10.1186/s12882-023-03326-8.
3
A Universal Bleeding Risk Score in Native and Allograft Kidney Biopsies: A French Nationwide Cohort Study.
自体肾活检和同种异体肾活检的通用出血风险评分:一项法国全国队列研究。
J Clin Med. 2023 May 17;12(10):3527. doi: 10.3390/jcm12103527.
4
Concordance of Solid Organ Biopsy Diagnoses With Hospital Autopsy and the Contribution of Biopsies to Death.实体器官活检诊断与医院尸检的一致性以及活检对死亡的影响。
Cureus. 2023 Jan 17;15(1):e33889. doi: 10.7759/cureus.33889. eCollection 2023 Jan.