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术前静止状态下的外阴裂孔大小能否预测手术结果?

Does preoperative resting genital hiatus size predict surgical outcomes?

机构信息

Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

J Obstet Gynaecol Res. 2021 Nov;47(11):4023-4029. doi: 10.1111/jog.14993. Epub 2021 Aug 19.

Abstract

AIM

To determine whether preoperative genital hiatus at rest is predictive of medium-term prolapse recurrence.

METHODS

We conducted a retrospective study of women who underwent native tissue prolapse surgery from 2002 to 2017 with pelvic organ prolapse quantification data including resting genital hiatus at one of three time points: preoperatively, 6 weeks, and ≥1 year postoperatively. Demographics and clinical data were abstracted from the chart. Prolapse recurrence was defined by anatomic outcomes (Ba > 0, Bp > 0, and/or C ≥ -4) or retreatment. Descriptive statistics, bivariate analyses, and logistic regression analyses were performed.

RESULTS

Of the 165 women included, 36 (21.8%) had prolapse recurrence at an average of 1.5 years after surgery. Preoperative resting genital hiatus did not differ between women with surgical success versus recurrence (3.5 cm [interquartile range, IQR 2.25, 4.0) vs 3.5 cm (IQR 3.0, 4.0), p = 0.71). Point Bp was greater in the recurrence group at every time point. Preoperative Bp (odds ratio [OR] 1.24, confidence interval [CI] [1.06-1.45], p = 0.01) and days from surgery (OR 1.001, CI [1.000-1.001], p < 0.01) were independently associated with recurrence. Preoperative genital hiatus at rest and strain were significantly larger among women who underwent a colpoperineorrhaphy (rest: 4.0 [3.0, 4.5] cm vs 3.5 [3.0, 4.0] cm, p < 0.01; strain: 6.0 [4.0, 6.5] cm vs 5.0 [4.0, 6.0] cm, p = 0.01).

CONCLUSIONS

Preoperative genital hiatus at rest was not associated with prolapse recurrence when the majority of women underwent colpoperineorrhaphy. Preoperative Bp was more predictive of short-term prolapse recurrence. For every 1 cm increase in point Bp, there is a 24% increased odds of recurrence.

摘要

目的

确定术前静止状态下的生殖器裂孔是否可预测中期脱垂复发。

方法

我们对 2002 年至 2017 年间接受天然组织脱垂手术的女性进行了回顾性研究,这些女性的盆腔器官脱垂量化数据包括术前、6 周和术后≥1 年的三个时间点的静止生殖器裂孔。从图表中提取人口统计学和临床数据。脱垂复发的定义为解剖学结果(Ba>0、Bp>0 和/或 C≥-4)或再次治疗。进行描述性统计、双变量分析和逻辑回归分析。

结果

在 165 名女性中,36 名(21.8%)在手术后平均 1.5 年内出现脱垂复发。手术成功与复发的女性之间,术前静止生殖器裂孔无差异(3.5cm [四分位距,IQR 2.25,4.0] 与 3.5cm [IQR 3.0,4.0],p=0.71)。每个时间点,复发组的点 Bp 更大。术前 Bp(比值比 [OR] 1.24,置信区间 [CI] [1.06-1.45],p=0.01)和手术天数(OR 1.001,CI [1.000-1.001],p<0.01)与复发独立相关。接受会阴修补术的女性的术前静止生殖器裂孔和张力明显更大(静止状态:4.0[3.0,4.5]cm 与 3.5[3.0,4.0]cm,p<0.01;张力:6.0[4.0,6.5]cm 与 5.0[4.0,6.0]cm,p=0.01)。

结论

当大多数女性接受会阴修补术时,术前静止状态下的生殖器裂孔与脱垂复发无关。术前 Bp 更能预测短期脱垂复发。点 Bp 每增加 1cm,复发的几率就增加 24%。

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