Mraovitch S, Seylaz J
Laboratoire de Physiologie et Physiopathologie Cérébrovasculaire, INSERM U. 182, C.N.R.S. U.A. 641, Université Paris VII, France.
Neurosci Lett. 1987 Dec 29;83(3):269-74. doi: 10.1016/0304-3940(87)90098-x.
Changes in local cerebral blood flow (1CBF) and local cerebral glucose utilization (1CGU) during electrical stimulation of the centromedian-parafascicular complex in rat have been determined using the autoradiographic [14C]iodoantipyrine and 2-deoxy-[14C]glucose methods. In 40 out of 47 cerebral regions measured, the centromedian-parafascicular complex (CM-Pf) stimulation elicited an increase in 1CBF. The increase in 1CBF was not associated with a rise in cerebral metabolism in 38 regions. Thus, it appears that the activation of CM-Pf neurons or fibers passing through it could play an important role in regulating primary cerebral vasodilation.
采用放射自显影术的[14C]碘安替比林和2-脱氧-[14C]葡萄糖方法,已测定了大鼠在电刺激中央中核-束旁复合体时局部脑血流量(1CBF)和局部脑葡萄糖利用率(1CGU)的变化。在所测量的47个脑区中的40个脑区,中央中核-束旁复合体(CM-Pf)刺激引起了1CBF增加。在38个脑区中,1CBF的增加与脑代谢的升高无关。因此,似乎CM-Pf神经元或穿过它的纤维的激活在调节原发性脑血管舒张中可能起重要作用。