Department of Paediatric and Neonatal Surgery, Royal Manchester Children's Hospital, Manchester, UK.
National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Arch Dis Child Fetal Neonatal Ed. 2022 Jul;107(4):448-450. doi: 10.1136/archdischild-2021-322040. Epub 2021 Aug 19.
Optimal timing for neonatal stoma closure remains unclear. In this study, we aimed to establish current practice and illustrate multidisciplinary perspectives on timing of stoma closure using an online survey sent to all 27 UK neonatal surgical units, as part of a research programme to determine the feasibility of a clinical trial comparing 'early' and 'late' stoma closure. 166 responses from all 27 units demonstrated concordance of opinion in target time for closure (6 weeks most commonly stated across scenarios), although there was a high variability in practice. A sizeable proportion (41%) of respondents use weight, rather than time, to determine when to close a neonatal stoma. Thematic analysis of free text responses identified nine key themes influencing decision-making; most related to nutrition, growth and stoma complications. These data provide an overview of current practice that is critical to informing an acceptable trial design.
新生儿造口关闭的最佳时机仍不清楚。本研究旨在通过向英国所有 27 家新生儿外科单位发送在线调查，利用在线调查来建立当前的实践，并展示对造口关闭时机的多学科观点，这是一项旨在确定比较“早期”和“晚期”造口关闭的临床试验可行性的研究计划的一部分。来自 27 个单位的 166 个回复显示，在目标关闭时间（大多数情况下在所有情况下都表示为 6 周）上存在意见一致，尽管实践中存在高度的可变性。相当一部分（41%）的受访者使用体重而不是时间来确定何时关闭新生儿造口。对自由文本回复的主题分析确定了影响决策的九个关键主题；大多数与营养、生长和造口并发症有关。这些数据提供了当前实践的概述，对于告知可接受的试验设计至关重要。
