A Comparison of Demographic and Psychosocial Characteristics Between Transgender Youth Enrolling Versus Not Enrolling in a Multisite Study.

To characterize demographics, psychosocial functioning, and gender-related experiences in transgender youth enrolling versus declining participation in a multisite research study. Clinical data were abstracted from patient charts at two study sites. Continuous variables were compared using -tests, and categorical variables were compared using tests based on study enrollment status. Few significant differences were observed between enrolled and nonenrolled youth. None of these differences (i.e., designated sex at birth/gender identity; parent-reported separation anxiety; and youth-reported attention deficit/hyperactivity disorder) was replicated across sites. Trans Youth Care findings are likely generalizable to transgender youth initiating hormone treatment at pediatric academic centers.