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被误诊为鼻后孔息肉的腺样囊性癌:一种罕见的表现。

ADENOID CYSTIC CARCINOMA MISINTERPRETED AS ANTROCHOANAL POLYP: A RARE PRESENTATION.

作者信息

Brar R K, Bharti J N, Nigam J S, Sehgal S

机构信息

Dept. of Pathology, Andaman & Nicobar Islands institute of Medical Sciences, Port Blair, India.

Dept. of Transfusion Medicine, Andaman & Nicobar Islands Institute of Medical Sciences, Port Blair, India.

出版信息

Ann Ib Postgrad Med. 2020 Dec;18(2):160-162.

PMID:34421458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8369394/
Abstract

Adenoid cystic Carcnoma (ACC) is an uncommon malignant tumour accounting for <1% of all oral and maxillofacial tumors. However, in the sinonasal tract, ACC is the most common salivary gland tumor. The sinonasal ACC is asymptomatic initially or causes non-specific symptoms that are similar to those caused by inflammatory sinus disease and local neurological symptoms such as trigeminal neuralgia in advance stage due to perineural invasion by the tumour.We present a case of 35-year-old female who presented with complaints of nasal obstruction and headache. CT scans revealed an antrochoanal polyp without any bony involvement. The histopathological examination revealed unremarkable respiratory epithelium with underlying sheets and acini of small hyperchromatic cells with hyaline-like material in the lumina, confirming adenoid cystic carcinoma. The highlight of this case is that sinonasal polyps are not always inflammatory in origin, these can be neoplastic also.

摘要

腺样囊性癌(ACC)是一种罕见的恶性肿瘤,占所有口腔颌面肿瘤的比例不到1%。然而,在鼻窦区域,ACC是最常见的涎腺肿瘤。鼻窦ACC最初通常无症状,或引起与炎性鼻窦疾病相似的非特异性症状,在疾病晚期,由于肿瘤的神经周围浸润,还会导致局部神经症状,如三叉神经痛。我们报告一例35岁女性患者,她因鼻塞和头痛前来就诊。CT扫描显示有一个鼻窦后鼻孔息肉,未累及任何骨质。组织病理学检查显示呼吸上皮无明显异常,其下方有小的深染细胞组成的片状和腺泡结构,管腔内有透明样物质,确诊为腺样囊性癌。该病例的亮点在于鼻窦息肉并非总是炎症性起源,也可能是肿瘤性的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d66/8369394/7b2f182cffce/AIPM-18-160_F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d66/8369394/7b2f182cffce/AIPM-18-160_F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d66/8369394/7b2f182cffce/AIPM-18-160_F1.jpg

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本文引用的文献

1
Sinonasal adenoid cystic carcinoma: a population-based analysis of 694 cases.鼻窦腺样囊性癌:基于人群的694例病例分析。
Int Forum Allergy Rhinol. 2017 Mar;7(3):312-320. doi: 10.1002/alr.21875. Epub 2016 Nov 11.
2
Adenoid cystic carcinoma of the head and neck: a single-institution's analysis of 45 consecutive cases over a 29-year period.头颈部腺样囊性癌:一家机构对29年间连续45例病例的分析。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Aug;122(2):152-7. doi: 10.1016/j.oooo.2016.03.007. Epub 2016 Mar 15.
3
An Unusual Presentation of Adenoid Cystic Carcinoma.
腺样囊性癌的一种不寻常表现。
Case Rep Otolaryngol. 2015;2015:826436. doi: 10.1155/2015/826436. Epub 2015 Dec 24.
4
Adenoid cystic carcinoma of the head and neck: a review.头颈部腺样囊性癌:综述
Curr Opin Otolaryngol Head Neck Surg. 2004 Apr;12(2):127-32. doi: 10.1097/00020840-200404000-00013.