Gill Kurren S, Frattali Mark A
The Commonwealth Medical College, 525 Pine Street, Scranton, PA 18509, USA.
The Commonwealth Medical College, 525 Pine Street, Scranton, PA 18509, USA; Delta Medix Ear, Nose & Throat, PC, 940 Jefferson Avenue, Scranton, PA 18510, USA.
Case Rep Otolaryngol. 2015;2015:826436. doi: 10.1155/2015/826436. Epub 2015 Dec 24.
Adenoid cystic carcinoma (ACC) is a relatively rare tumor of epithelial cell origin, most commonly arising from major salivary glands. It is uncommonly found outside the major or minor salivary glands and is especially rare when located in the nasal cavity. Diagnosis and treatment of ACC pose numerous challenges, partly due to its biological behavior of slow growth, high tendency of local recurrence, and perineural invasion. We present the case of a 67-year-old male with complaints of facial pain and swelling, with a CT scan showing a soft tissue mass extending from the right nasal cavity with osseous destruction. Biopsy revealed ACC with perineural invasion. ACC of the nasal cavity continues to pose diagnostic and therapeutic challenges to physicians. Because this rare pathology presents in a vague manner, early diagnosis requires a high index of suspicion for this disease and close follow-up care. Since ACC of the nasal cavity is seldom reported in the literature, it is our hope that reporting these rare instances as case reports will heighten physician awareness of this rare disease, allowing for early diagnosis and treatment.
腺样囊性癌（ACC）是一种相对罕见的上皮细胞起源肿瘤，最常见于大唾液腺。在大、小唾液腺以外的部位很少见，位于鼻腔时尤为罕见。ACC的诊断和治疗面临诸多挑战，部分原因是其生长缓慢、局部复发倾向高以及神经侵犯的生物学行为。我们报告一例67岁男性，主诉面部疼痛和肿胀，CT扫描显示一个软组织肿块从右侧鼻腔延伸并伴有骨质破坏。活检显示为伴有神经侵犯的ACC。鼻腔ACC对医生来说仍然是诊断和治疗上的挑战。由于这种罕见的病理表现不明确，早期诊断需要对该疾病有高度的怀疑指数并密切随访。由于鼻腔ACC在文献中很少报道，我们希望通过病例报告的形式报道这些罕见病例能够提高医生对这种罕见疾病的认识，从而实现早期诊断和治疗。
