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某些淡水鱼红细胞和肝脏中抗氧化酶与脂质过氧化的比较研究

Comparative antioxidant enzyme and lipid peroxidation study in erythrocytes and liver of some freshwater fish.

作者信息

Gabryelak T, Pérès G

机构信息

Department of Biophysics, University of Ludz, Poland.

出版信息

Acta Biol Hung. 1986;37(3-4):219-24.

PMID:3442172
Abstract
  1. Superoxide dismutase (SOD), catalase (C), peroxidase (P) and glutathione peroxidase (GSH-Px) were estimated in the erythrocytes and liver of the carp, the tench and the crucian carp during a two-years period, 1983-1984 (autumn). 2. The lipid peroxidation (LP) of the erythrocytes and liver homogenates was also compared. 3. The activities of the enzymes examined showed significant interspecies variations. 4. Significant differences were observed between enzyme activities (except for SOD in the liver) and lipid peroxidation in erythrocytes and liver of investigated fish species. 5. The very high values of peroxide enzyme activities in fish erythrocytes and SOD in fish liver suggest the predominant role of these enzymes in protection of polyunsaturated acids against uncontrolled oxidative processes.
摘要
  1. 在1983年至1984年(秋季)的两年时间里,对鲤鱼、丁鱥和鲫鱼的红细胞及肝脏中的超氧化物歧化酶(SOD)、过氧化氢酶(C)、过氧化物酶(P)和谷胱甘肽过氧化物酶(GSH-Px)进行了测定。2. 还比较了红细胞和肝脏匀浆的脂质过氧化(LP)情况。3. 所检测酶的活性显示出显著的种间差异。4. 在被调查鱼类的红细胞和肝脏中,酶活性(肝脏中的SOD除外)与脂质过氧化之间存在显著差异。5. 鱼类红细胞中过氧化物酶活性和鱼肝中SOD活性的值非常高,表明这些酶在保护多不饱和酸免受不受控制的氧化过程中起主要作用。

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