Yoshimura T, Miyoshi T, Imaki M, Tamura T, Fujii M, Hori Y, Itou S, Nakamura T, Takahashi H, Tanada M
Dept. of Public Health, School of Medicine, Univ. of Tokushima, Japan.
Acta Biol Hung. 1986;37(3-4):243-8.
Changes in the activity of serum lactate dehydrogenase (LDH) and the serum LDH isozyme pattern in healthy young men given a high carbohydrate diet (480-636 g/day, 80% of the total energy) for 21 days were examined. Serum total LDH activity showed no significant change in four healthy young volunteers who received high carbohydrate diet for 21 days. However, the percentage of LDH-4 increased significantly (P less than 0.01) from 8.5 +/- 2.4 to 10.9 +/- 1.9% after 21 days, as did also the percentage of LDH-5 (P less than 0.01) from 5.1 +/- 1.9 to 10.7 +/- 2.9%. The percentage of M-type LDH activity increased 30% during the experiment (P less than 0.05). It is concluded from the results that the high carbohydrate intake affects the percentage of LDH-4 and LDH-5, but not the total serum LDH activity.
研究了健康年轻男性在摄入高碳水化合物饮食（480 - 636克/天，占总能量的80%）21天后血清乳酸脱氢酶（LDH）活性及血清LDH同工酶谱的变化。在接受21天高碳水化合物饮食的四名健康年轻志愿者中，血清总LDH活性无显著变化。然而，21天后，LDH - 4的百分比从8.5±2.4显著增加至10.9±1.9%（P＜0.01），LDH - 5的百分比也从5.1±1.9显著增加至10.7±2.9%（P＜0.01）。实验期间M型LDH活性百分比增加了30%（P＜0.05）。结果表明，高碳水化合物摄入会影响LDH - 4和LDH - 5的百分比，但不影响血清总LDH活性。
