Hopkins D R, Flórez D
Int J Epidemiol. 1977 Dec;6(4):349-55. doi: 10.1093/ije/6.4.349.
Three treponemal infections of man have coexisted in Colombia, South America for centuries. In former years, Colombia and Mexico were the world's most highly endemic countries for pinta. Within Colombia, highest rates of infection with pinta occurred among the mestizo and Indian populations in the Andean and Caribbean departments of Huila, Tolima, Antiochia, Magdalena and Cesar. Yaws occurred primarily in rural areas along the Pacific coast among descendants of African slaves. Infectious syphilis is most often reported from the three largest urban areas, and from three other densely populated departments in the Andean region. During the 21-year period from 1954 to 1974, almost four times as many cases of pinta as yaws were reported. The incidence rates of yaws and pinta have declined almost in parallel in Colombia, even though there has been a national campaign against yaws, but not against pinta. The incidence of primary and secondary syphilis increased only slightly during the same period. The total burden of reported treponematoses (excluding tertiary and congenital syphilis) declinded by over 40 per cent, while the ratios of reported yaws, pinta and infectious syphilis rose from 1:3:4 in 1954 to 1:7:975 in 1974.
在南美洲的哥伦比亚,三种人类密螺旋体感染并存已有数百年。前些年,哥伦比亚和墨西哥曾是世界上品他病流行最严重的国家。在哥伦比亚境内,品他病感染率最高的是在安第斯和加勒比地区的乌伊拉、托利马、安蒂奥基亚、马格达莱纳和塞萨尔等省的混血儿和印第安人群体中。雅司病主要发生在太平洋沿岸农村地区非洲奴隶的后裔中。传染性梅毒大多报告来自三个最大的城市地区以及安第斯地区其他三个人口密集的省份。在1954年至1974年的21年期间,报告的品他病病例几乎是雅司病病例的四倍。在哥伦比亚,雅司病和品他病的发病率几乎同步下降,尽管该国开展了一场防治雅司病的运动,但没有防治品他病的运动。同期,一期和二期梅毒的发病率仅略有上升。报告的密螺旋体病(不包括三期和先天性梅毒)总负担下降了40%以上,而报告的雅司病、品他病和传染性梅毒的比例从1954年的1:3:4上升到了1974年的1:7:975。