Blümchen G, Valdivieso E, Jetté M, Landry F
Klinik Roderbirken, Leichlingen, Federal Republic of Germany.
Eur Heart J. 1987 Oct;8 Suppl G:39-42. doi: 10.1093/eurheartj/8.suppl_g.39.
The purpose of this study was to determine if isometric exercise (handgrip) using a substantial muscle mass and intensity could be substituted for dynamic exercise in the assessment of left ventricular function in myocardial infarct (MI) patients. Forty patients with documented MI were assigned, on the basis of their previous exercise ECG responses, to either an exercise-induced ischaemic group (Group 1) or to a non-exercise ischaemic group (Group 2). Eight apparently healthy males served as controls. Pulmonary capillary pressure (PCP) was measured at rest, during volume loading and during isometric and dynamic exercise. Mean PCP in Group 1 increased progressively from 7.5 +/- 2.9 mmHg at rest, to 11.6 +/- 3.8 mmHg during volume loading, to 18.8 +/- 10.2 mmHg during the isometric exercise and to 25.2 +/- 10.1 mmHg during the dynamic exercises. For Group 2, the respective values were 9.6 +/- 6.3, 13.1 +/- 6.4, 18.7 +/- 13.7 and 18.4 +/- 9.8 and for the controls 8.9 +/- 1.9, 11.3 +/- 1.2, 13.3 +/- 3.3 and 11.8 +/- 3.6 mmHg. The results of this study indicate that isometric exercise of 50% MVC using both hands can adequately replace dynamic exercise in the diagnosis of left ventricular function in post MI patients.
本研究的目的是确定在评估心肌梗死（MI）患者的左心室功能时，使用大量肌肉群和强度的等长运动（握力）是否可以替代动态运动。根据40例有MI记录的患者之前的运动心电图反应，将他们分为运动诱发缺血组（第1组）或非运动缺血组（第2组）。8名明显健康的男性作为对照组。在静息、容量负荷、等长运动和动态运动期间测量肺毛细血管压（PCP）。第1组的平均PCP从静息时的7.5±2.9 mmHg逐渐增加到容量负荷时的11.6±3.8 mmHg，等长运动时的18.8±10.2 mmHg和动态运动时的25.2±10.1 mmHg。第2组的相应值分别为9.6±6.3、13.1±6.4、18.7±13.7和18.4±9.8，对照组为8.9±1.9、11.3±1.2、13.3±3.3和11.8±3.6 mmHg。本研究结果表明，双手进行50%最大随意收缩（MVC）的等长运动可以在诊断MI后患者的左心室功能时充分替代动态运动。
