Buxton F P, Gwynne D I, Garven S, Sibley S, Davies R W
Allelix Incorporated, Mississauga, Ont., Canada.
Gene. 1987;60(2-3):255-65. doi: 10.1016/0378-1119(87)90234-4.
We have cloned the gene encoding ornithine carbamoyl transferase (OCTase) from Aspergillus niger. The structure and complete nucleotide sequence of this gene have been determined. The gene encodes an mRNA of 1.3 kb. The transcription unit contains an open reading frame of 1110 nucleotides (nt) which shows strong homology to the OCTase of Aspergillus nidulans along most of its length. The N terminus, which shows little or no homology to other OCTases, is highly basic and is probably involved in mitochondrial targeting.
我们已经从黑曲霉中克隆出编码鸟氨酸氨甲酰基转移酶（OCTase）的基因。该基因的结构和完整核苷酸序列已被确定。该基因编码一个1.3 kb的mRNA。转录单元包含一个1110个核苷酸（nt）的开放阅读框，其大部分长度与构巢曲霉的OCTase具有很强的同源性。N端与其他OCTase几乎没有同源性，具有高度碱性，可能参与线粒体靶向。
