通过一名15岁儿童牙周病变诊断的朗格汉斯细胞组织细胞增多症：病例报告

Langerhans' Cell Histiocytosis Diagnosed through Periodontal Lesion in a 15-year-old Child: A Case Report.

作者信息

Soangra Rajeev, Kapoor Anjali, Meena Deepak, Sharma Meenakshi, Sankhla Bharat

机构信息

Department of Periodontics, Government Dental College, Jaipur, Rajasthan, India.

Department of Dentistry, SPMC Medical College, Bikaner, Rajasthan, India.

出版信息

Int J Clin Pediatr Dent. 2020;13(Suppl 1):S115-S118. doi: 10.5005/jp-journals-10005-1875.

DOI:10.5005/jp-journals-10005-1875

PMID:34434026

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8359874/

Abstract

Langerhans' cell histiocytosis (LCH) is a rare disease of the reticuloendothelial system in which there are abnormal proliferation and accumulation of histiocytes, abnormal cells deriving from bone marrow that can migrate from the skin to the lymph nodes. Langerhans' cell histiocytosis has three variants: unifocal (eosinophilic granuloma), multifocal unisystem (Hand-Schuller-Christian triad), and multifocal multisystem (Letterer-Siwe disease). We present a case of oral lesions associated with LCH in a young male aged 15 years. The history, radiological appearance, histopathology, and treatment options of the patient are discussed. Soangra R, Kapoor A, Meena D, Langerhans' Cell Histiocytosis Diagnosed through Periodontal Lesion in a 15-year-old Child: A Case Report. Int J Clin Pediatr Dent 2020;13(S-1):S115-S118.

摘要

朗格汉斯细胞组织细胞增多症（LCH）是一种罕见的网状内皮系统疾病，其中组织细胞异常增殖和积聚，这些异常细胞源自骨髓，可从皮肤迁移至淋巴结。朗格汉斯细胞组织细胞增多症有三种变体：单灶性（嗜酸性肉芽肿）、多灶性单系统（汉-许-克三联征）和多灶性多系统（勒-雪病）。我们报告一例15岁年轻男性与朗格汉斯细胞组织细胞增多症相关的口腔病变病例。讨论了该患者的病史、影像学表现、组织病理学及治疗选择。Soangra R, Kapoor A, Meena D, 15岁儿童经牙周病变诊断为朗格汉斯细胞组织细胞增多症：一例报告。《国际临床儿科牙科学杂志》2020年；13（S-1）：S115-S118 。