Bashiruddin J B, Martin J L
Department of Microbiology, Monash University Medical School, Prahran, Vic., Australia.
Intervirology. 1987;28(2):122-4. doi: 10.1159/000150005.
In Boolarra virus infected Drosophila line 1 cells five virus-induced proteins were readily detected 20 h postinfection. These were A (103,500), alpha (46,000), beta (40,000), B (9,600), and gamma (6,600) and are similar in molecular weight to those induced in vivo by other nodaviruses. The addition of actinomycin D for the 1st h before the labeling period resulted in the production of all five proteins; but when actinomycin D was introduced for the entire labeling period, the synthesis of the products of RNA1 was greatly reduced. Host functions inhibited by actinomycin D may play a major role in the replication of this virus.
在感染了博拉腊病毒的果蝇1型细胞中，感染后20小时很容易检测到五种病毒诱导蛋白。它们分别是A（103,500）、α（46,000）、β（40,000）、B（9,600）和γ（6,600），其分子量与其他诺达病毒在体内诱导产生的蛋白相似。在标记期前第1小时添加放线菌素D会产生所有五种蛋白；但当在整个标记期都加入放线菌素D时，RNA1产物的合成会大大减少。被放线菌素D抑制的宿主功能可能在这种病毒的复制中起主要作用。
