High-performance liquid chromatographic method for the analysis of debrisoquine and its S-(+)- and R-(-)-hydroxy metabolites in urine.
作者信息
Meese C O, Thalheimer P, Eichelbaum M
机构信息
Dr. Margarete Fischer-Bosch-Institut für Klinische Pharmakologie, Stuttgart, F.R.G.
出版信息
J Chromatogr. 1987 Dec 25;423:344-50. doi: 10.1016/0378-4347(87)80362-6.
PMID:3443671
Abstract
摘要
相似文献
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High-performance liquid chromatographic method for the analysis of debrisoquine and its S-(+)- and R-(-)-hydroxy metabolites in urine.高效液相色谱法分析尿液中的异喹胍及其S-(+)-和R-(-)-羟基代谢物。
J Chromatogr. 1987 Dec 25;423:344-50. doi: 10.1016/0378-4347(87)80362-6.
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Liquid chromatographic method for the determination of debrisoquine and its 4-hydroxy metabolite in human urine.液相色谱法测定人尿中异喹胍及其4-羟基代谢物
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Determination of debrisoquine and its 4-hydroxy metabolite in urine by high-performance liquid chromatography.高效液相色谱法测定尿中异喹胍及其4-羟基代谢物
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The effect of urine pH on debrisoquine phenotyping: application of an HPLC-method.尿液pH值对异喹胍表型分析的影响：高效液相色谱法的应用
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Liquid chromatographic assay for debrisoquine and 4-hydroxydebrisoquine in urine.尿液中去甲丙咪嗪和4-羟基去甲丙咪嗪的液相色谱测定法。
J Chromatogr. 1986 Jan 10;374(1):200-3. doi: 10.1016/s0378-4347(00)83272-7.
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Direct determination of debrisoquine and 4-hydroxydebrisoquine using a high-performance liquid chromatographic switching technique.使用高效液相色谱切换技术直接测定去甲丙咪嗪和4-羟基去甲丙咪嗪。
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Stereoselectivity of the 4-hydroxylation of debrisoquine in man, detected by gas chromatography/mass spectrometry.
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Assay of debrisoquine and 4-hydroxydebrisoquine in urine by reversed-phase high-performance liquid chromatography using on-line sample clean-up on a standard isocratic chromatograph.使用标准等度色谱仪上的在线样品净化，通过反相高效液相色谱法测定尿液中的异喹胍和4-羟基异喹胍。
J Chromatogr. 1988 Jun 24;428(1):178-82. doi: 10.1016/s0378-4347(00)83905-5.
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Rapid liquid chromatographic determination of debrisoquine and its hydroxy metabolite in human urine to define hydroxylation phenotypes.快速液相色谱法测定人尿中去甲异喹胍及其羟基代谢物以确定羟基化表型。
J Chromatogr. 1987 Dec 25;423:340-3. doi: 10.1016/0378-4347(87)80361-4.
引用本文的文献
1
Enantioselectivity of 4-hydroxylation in extensive and poor metabolizers of debrisoquine.异喹胍广泛代谢者和慢代谢者中4-羟化反应的对映体选择性。
Br J Clin Pharmacol. 1988 Apr;25(4):505-8. doi: 10.1111/j.1365-2125.1988.tb03335.x.
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