LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Molecules. 2021 Aug 18;26(16):4989. doi: 10.3390/molecules26164989.
Pyrazoles and their reduced form, pyrazolines, are considered privileged scaffolds in medicinal chemistry, owing to their remarkable biological activities, physicochemical properties and occurrence in many low-molecular-weight compounds present in several marketed drugs (e [...].
吡唑及其还原形式吡唑啉被认为是药物化学中的优势骨架,因为它们具有显著的生物活性、物理化学性质,并且存在于许多市售药物中的许多低分子量化合物中(...)。