Department of Organic Chemistry, University of Chemistry and Technology, 16628 Prague, Czech Republic.
Molecules. 2021 Aug 22;26(16):5079. doi: 10.3390/molecules26165079.
This review summarizes the current state-of-the-art procedures in terms of the preparation of -arylindoles. After a short introduction, the transition-metal-free procedures available for the -arylation of indoles are briefly discussed. Then, the nickel-catalyzed and palladium-catalyzed -arylation of indoles are both discussed. In the next section, copper-catalyzed procedures for the -arylation of indoles are described. The final section focuses on recent findings in the field of biologically active -arylindoles.
这篇综述总结了 - 芳基吲哚制备的最新技术。在简短的引言之后，简要讨论了吲哚芳基化的无过渡金属方法。然后，讨论了镍催化和钯催化的吲哚芳基化。在下一节中，描述了吲哚铜催化芳基化的方法。最后一节重点介绍了生物活性 - 芳基吲哚领域的最新发现。
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