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基于摄像的帕金森病步态特征的客观测量。

Camera-based objective measures of Parkinson's disease gait features.

机构信息

Eindhoven University of Technology, 5612 AJ, Eindhoven, The Netherlands.

Motognosis GmbH, Schönhauser Allee 177, 10119, Berlin, Germany.

出版信息

BMC Res Notes. 2021 Aug 26;14(1):329. doi: 10.1186/s13104-021-05744-z.

Abstract

OBJECTIVE

Parkinson's disease is a common, age-related, neurodegenerative disease, affecting gait and other motor functions. Technological developments in consumer imaging are starting to provide high-quality, affordable tools for home-based diagnosis and monitoring. This pilot study aims to investigate whether a consumer depth camera can capture changes in gait features of Parkinson's patients. The dataset consisted of 19 patients (tested in both a practically defined OFF phase and ON phase) and 8 controls, who performed the "Timed-Up-and-Go" test multiple times while being recorded with the Microsoft Kinect V2 sensor. Camera-derived features were step length, average walking speed and mediolateral sway. Motor signs were assessed clinically using the Movement Disorder Society Unified Parkinson's Disease Rating Scale.

RESULTS

We found significant group differences between patients and controls for step length and average walking speed, showing the ability to detect Parkinson's features. However, there were no differences between the ON and OFF medication state, so further developments are needed to allow for detection of small intra-individual changes in symptom severity.

摘要

目的

帕金森病是一种常见的、与年龄相关的神经退行性疾病,影响步态和其他运动功能。消费类成像技术的发展开始为基于家庭的诊断和监测提供高质量、经济实惠的工具。本试点研究旨在调查消费级深度相机是否可以捕捉帕金森病患者步态特征的变化。该数据集包括 19 名患者(在实际定义的“关”期和“开”期均进行了测试)和 8 名对照者,他们在使用 Microsoft Kinect V2 传感器多次进行“起立-行走计时测试”时被记录下来。相机获得的特征包括步长、平均行走速度和横向摆动。运动障碍协会统一帕金森病评定量表(Movement Disorder Society Unified Parkinson's Disease Rating Scale)用于临床评估运动迹象。

结果

我们发现患者与对照组在步长和平均行走速度方面存在显著的组间差异,表明能够检测到帕金森病的特征。然而,在药物“开”和“关”状态之间没有差异,因此需要进一步的开发,以允许检测症状严重程度的微小个体内变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8784/8393451/451d5f93aa57/13104_2021_5744_Fig1_HTML.jpg

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