Flies in the ointment: AAV vector preparations and tumor risk.
作者信息
Zhang Junping, Yu Xiangping, Herzog Roland W, Samulski R Jude, Xiao Weidong
机构信息
Herman B Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
出版信息
Mol Ther. 2021 Sep 1;29(9):2637-2639. doi: 10.1016/j.ymthe.2021.08.016. Epub 2021 Aug 26.
Abstract
摘要
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Long-Term Follow-Up of the First in Human Intravascular Delivery of AAV for Gene Transfer: AAV2-hFIX16 for Severe Hemophilia B.首例体内血管内给药的腺相关病毒基因治疗的长期随访：用于严重血友病 B 的 AAV2-hFIX16。
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