[Karyotype in fortuitous familial meningioma. Report of 2 cases].

The authors report a case of two sisters affected of intracranial meningioma, with no evidence of von Recklinghausen's disease. A study of the karyotype has been performed in the patients and in their family; in one sister we have found a pericentric inversion of one chromosome 9. The possible role of the chromosomal abnormality in the develop of familial meningioma is discussed.