Ferrante L, Acqui M, Mastronardi L, Nucci F
Department of Neurological Sciences, University of Rome La Sapienza, Italy.
J Neurosurg Sci. 1987 Jul-Sep;31(3):145-51.
The Authors report a case of intracranial meningioma in two sisters, with no evidence of neurofibromatosis. A study of the karyotype has been performed; in one patient we have found a pericentric inversion of one chromosome 9. The possible role of the genetical factors in the develop of familial meningiomas is discussed.
作者报告了两姐妹患颅内脑膜瘤的病例,未发现神经纤维瘤病迹象。已对核型进行了研究;在一名患者中发现一条9号染色体发生了臂间倒位。文中讨论了遗传因素在家族性脑膜瘤发生中的可能作用。