Laboratory of Medical Expert Systems "Anthropos Systems Lab.", Vinnitsa, Ukraine.
Privolzhsky Research Medical University, Nizhny Novgorod, Russia.
J Physiol Anthropol. 2021 Aug 27;40(1):9. doi: 10.1186/s40101-021-00260-2.
Applying human biological evolution to solve topical problems of medicine and preventive cardiology was inspired by the realization of the need for clinical and experimental studies of biological (evolutionary) prerequisites in the occurrence of a pathology. Although it has been stated that there is a need to provide a full biological understanding of features, including those that increase an animal's vulnerability to diseases, unfortunately, in this regard, erectile and associated adaptations to the Earth's gravity in their physiological and pathological manifestations have not been considered. At the same time, it should be noted that humans, unlike other animal species, have the greatest vulnerability of the cardiovascular system (CVS). The latter is associated with fundamental differences in the functioning and regulation of the CVS by the influence of gravity on blood circulation in humans as upright creatures. Based on a review of comparative physiological, ontogenetic, and clinical studies from an evolutionary perspective, the idea of adaptation to the Earth's gravity when walking upright in humans is justified as an anthropogenic basis for the physiology and pathology of the cardiovascular system and hemodynamic support systems (physio-anthropology and pathological anthropology).
将人类生物进化应用于解决医学和预防心脏病学的当前问题的灵感来自于认识到需要对病理学发生的生物学（进化）先决条件进行临床和实验研究。尽管已经指出有必要提供对特征的全面生物学理解，包括那些增加动物对疾病易感性的特征，但不幸的是，在这方面，没有考虑到与勃起和与地球重力相关的适应在其生理和病理表现中的作用。同时，应当指出，与其他动物物种不同，人类的心血管系统（CVS）最脆弱。后者与 CVS 的功能和调节受到重力对人类直立生物血液循环的影响有关。基于从进化角度对比较生理学、个体发生学和临床研究的回顾，直立行走时适应地球重力的观点被认为是心血管系统生理学和病理学以及血液动力学支持系统（生理人类学和病理人类学）的人为基础。
