癌症相关的心理社会因素与妇科癌症幸存者生活方式的自我报告变化：PROFILES 注册研究数据的横断面分析。
Cancer-related psychosocial factors and self-reported changes in lifestyle among gynecological cancer survivors: cross-sectional analysis of PROFILES registry data.
机构信息
The Netherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands.
Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands.
出版信息
Support Care Cancer. 2022 Feb;30(2):1199-1207. doi: 10.1007/s00520-021-06433-0. Epub 2021 Aug 28.
PURPOSE
Obesity is prevalent in gynecological cancer survivors and is associated with impaired health outcomes. Concerns due to cancer and its treatment may impact changes in lifestyle after cancer. This study aimed to assess the association between cancer-related psychosocial factors and changes in physical activity and diet, 18 months after initial treatment among gynecological cancer survivors.
METHODS
Cross-sectional data from the ROGY Care study were used, including endometrial and ovarian cancer patients treated with curative intent. The Impact of Cancer Scale (IOCv2) was used to assess cancer-related psychosocial factors. Self-reported changes in nutrients/food groups and in physical activity post-diagnosis were classified into change groups (less/equal/more). Multivariable logistic regression models were used to assess associations.
RESULTS
Data from 229 cancer survivors (59% endometrial, 41% ovarian, mean age 66 ± 9.5, 70% tumor stage I) were analyzed. In total, 20% reported to eat healthier from diagnosis up to 18 months after initial treatment, 17% reported less physical activity and 20% more physical activity. Health awareness (OR 2.79, 95% CI: 1.38; 5.65), body change concerns (OR 3.04 95% CI: 1.71; 5.39), life interferences (OR 4.88 95% 2.29; 10.38) and worry (OR 2.62, 95% CI: 1.42; 4.85) were significantly associated with less physical activity up to 18 months after initial treatment whereby gastrointestinal symptoms were an important confounder.
CONCLUSION(S): This study underlines the need to raise awareness of the benefits of a healthy lifestyle and to provide tailored lifestyle advice, taking into account survivors' health awareness, body change concerns, life interferences, worry and gastrointestinal symptoms, in order to improve health behavior among gynecological cancer survivors.
TRIAL REGISTRATION
http://clinicaltrials.gov Identifier: NCT01185626, August 20, 2010.
目的
肥胖在妇科癌症幸存者中很普遍，与健康状况不佳有关。由于癌症及其治疗引起的担忧可能会影响癌症后的生活方式改变。本研究旨在评估妇科癌症幸存者在初始治疗后 18 个月时，与癌症相关的心理社会因素与体力活动和饮食变化之间的关联。
方法
使用 ROGY Care 研究的横断面数据，包括接受根治性治疗的子宫内膜癌和卵巢癌患者。使用癌症相关心理社会因素量表（IOCv2）评估癌症相关心理社会因素。自我报告的诊断后营养/食物组和体力活动的变化分为变化组（更少/相等/更多）。使用多变量逻辑回归模型评估关联。
结果
分析了 229 名癌症幸存者的数据（59%为子宫内膜癌，41%为卵巢癌，平均年龄 66±9.5，70%为肿瘤 I 期）。总的来说，有 20%的人报告从诊断开始到初始治疗后 18 个月内吃得更健康，17%的人报告体力活动减少，20%的人报告体力活动增加。健康意识（OR 2.79，95%CI：1.38；5.65）、身体变化担忧（OR 3.04，95%CI：1.71；5.39）、生活干扰（OR 4.88，95% 2.29；10.38）和担忧（OR 2.62，95%CI：1.42；4.85）与初始治疗后 18 个月内体力活动减少显著相关，其中胃肠道症状是一个重要的混杂因素。
结论
本研究强调需要提高对健康生活方式益处的认识，并提供量身定制的生活方式建议，同时考虑到幸存者的健康意识、身体变化担忧、生活干扰、担忧和胃肠道症状，以改善妇科癌症幸存者的健康行为。
试验注册
http://clinicaltrials.gov Identifier：NCT01185626，2010 年 8 月 20 日。
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