Robertson J H, Woodend B E, Crozier E H, Patterson A
Ulster Med J. 1987 Oct;56(2):90-4.
Eight hundred and ninety-six patients were followed up cytologically for up to 21 years following treatment for a CIN III lesion of the cervix. The recurrence rate (8.8%) was lower after hysterectomy than after treatment which preserved the cervix (23%). Long-term yearly follow-up is not required as all recurrences were detected by annual smears for a seven-year period after treatment in both groups. It is important to keep patients under cytological review following hysterectomy because of the appreciable recurrence rate and also evidence that intraepithelial lesions of the vaginal vault behave in an aggressive fashion.
896例宫颈原位癌（CIN III）患者接受治疗后，进行了长达21年的细胞学随访。子宫切除术后的复发率（8.8%）低于保留宫颈的治疗方法（23%）。两组患者在治疗后的7年里，通过每年的涂片检查发现了所有复发情况，因此无需进行长期的年度随访。子宫切除术后对患者进行细胞学检查很重要，因为复发率相当可观，而且有证据表明阴道穹窿的上皮内病变具有侵袭性。
