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Cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids contribute to insulin sensitivity in mice and in humans.
Diabetologia. 2017 Jun;60(6):1066-1075. doi: 10.1007/s00125-017-4260-0. Epub 2017 Mar 28.
2
Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers.
Chest. 2017 Mar;151(3):555-563. doi: 10.1016/j.chest.2016.10.058. Epub 2016 Nov 21.
3
Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor.
Br J Clin Pharmacol. 2016 May;81(5):971-9. doi: 10.1111/bcp.12855. Epub 2016 Jan 17.
4
Oxidative stress in chronic vascular disease: From prediction to prevention.
Vascul Pharmacol. 2015 Nov;74:23-37. doi: 10.1016/j.vph.2015.09.003. Epub 2015 Sep 10.
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The Epoxyeicosatrienoic Acid Pathway Enhances Hepatic Insulin Signaling and is Repressed in Insulin-Resistant Mouse Liver.
Mol Cell Proteomics. 2015 Oct;14(10):2764-74. doi: 10.1074/mcp.M115.049064. Epub 2015 Jun 12.
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CYP2J2 and EETs protect against lung ischemia/reperfusion injury via anti-inflammatory effects in vivo and in vitro.
Cell Physiol Biochem. 2015;35(5):2043-54. doi: 10.1159/000374011. Epub 2015 Mar 30.
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Epoxyeicosatrienoic acids, hypertension, and kidney injury.
Hypertension. 2015 Mar;65(3):476-82. doi: 10.1161/HYPERTENSIONAHA.114.03585. Epub 2015 Jan 12.
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Epoxyeicosatrienoic acids mediate insulin-mediated augmentation in skeletal muscle perfusion and blood volume.
Am J Physiol Endocrinol Metab. 2014 Dec 15;307(12):E1097-104. doi: 10.1152/ajpendo.00216.2014. Epub 2014 Oct 21.
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Arg287Gln variant of EPHX2 and epoxyeicosatrienoic acids are associated with insulin sensitivity in humans.
Prostaglandins Other Lipid Mediat. 2014 Oct;113-115:38-44. doi: 10.1016/j.prostaglandins.2014.08.001. Epub 2014 Aug 28.
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The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt.
J Biol Chem. 2014 Feb 14;289(7):4377-86. doi: 10.1074/jbc.M113.508416. Epub 2013 Dec 24.

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