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胎儿酒精谱系障碍的神经认知和行为特征。

Neurocognitive and behavioral profile of fetal alcohol spectrum disorder.

机构信息

Servicio de Neonatología, Hospital Clínic-Maternitat, ICGON, BCNatal, Barcelona, Spain.

Servicio de Neonatología, Hospital Clínic-Maternitat, ICGON, BCNatal, Barcelona, Spain; Departamento de Cirugía y Especialidades Medicoquirúrgicas, Universidad de Barcelona, Barcelona, Spain.

出版信息

An Pediatr (Engl Ed). 2021 Sep;95(3):208.e1-208.e9. doi: 10.1016/j.anpede.2020.12.012. Epub 2021 Aug 27.

Abstract

Prenatal alcohol exposure is the leading preventable cause of cognitive deficit in developed countries and can lead to fetal alcohol spectrum disorder (FASD). This term encompasses a wide range of physical, mental, behavioral, and cognitive effects that result from damage caused by exposure to alcohol during intrauterine life. Alcohol consumption among the general population is common in Eastern European countries and especially among women at risk of social exclusion, who are the ones who lose or give up custody of their children. A high number of these children are adopted in Spain and many of them present neurocognitive and behavioral disorders, causing FASD to be a public health problem in our country. In many occasions this clinical spectrum is delayed or under-diagnosed due to the overlapping of neuropsychological symptoms caused by the abandonment. A neurocognitive and behavioral profile specific for FASD has not been defined and all the symptoms are common to other etiologies. The aim of this work is to review the neuropsychological profile in the diagnosis of FASD.

摘要

产前酒精暴露是发达国家可预防的认知缺陷的主要原因,并可能导致胎儿酒精谱系障碍(FASD)。这一术语涵盖了一系列身体、精神、行为和认知方面的影响,这些影响是由宫内生活中接触酒精造成的损害引起的。在东欧国家,普通人群的饮酒现象很普遍,尤其是那些有社会排斥风险的妇女,她们往往失去或放弃对子女的监护权。其中许多儿童在西班牙被收养,他们中的许多人存在神经认知和行为障碍,导致 FASD 成为我国的一个公共卫生问题。在许多情况下,由于遗弃引起的神经心理症状的重叠,这种临床谱系被延迟或诊断不足。尚未确定针对 FASD 的特定神经认知和行为特征,所有症状都与其他病因共同存在。这项工作的目的是回顾在 FASD 诊断中的神经心理学特征。

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