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[儿童肠内诱导生长障碍时小肠固有层黏膜肥大细胞含量的变化]

[Changes in the mast cell content of the lamina propria mucosa of the small intestine in enteral-induced growth disorders in childhood].

作者信息

Pfister C, Scheuner G, Glede G, Schön E

机构信息

Institut für Anatomie des Bereichs Medizin (Charité), Humboldt-Universität zu Berlin, DDR.

出版信息

Zentralbl Allg Pathol. 1987;133(6):527-32.

PMID:3445714
Abstract

Duodenal jejeunal biopsy material from children with growth retardation due to enteric disease was investigated. The disease dependent mucosa types were classified into three groups according to Shmerling (1970). Mucosa types and established histological alterations can be correlated. Toluidine blue staining sections were analyzed morphometrically by light microscopy to study changes in the mucosal mast cells. The mast cell content in specimens with subtotal villal atrophy (type III) was reduced significantly compared to normal mucosa (type I).

摘要

对患有肠道疾病导致生长发育迟缓的儿童的十二指肠空肠活检材料进行了研究。根据施梅林(1970年)的方法,将与疾病相关的黏膜类型分为三组。黏膜类型与已确定的组织学改变具有相关性。通过光学显微镜对甲苯胺蓝染色切片进行形态计量分析,以研究黏膜肥大细胞的变化。与正常黏膜(I型)相比,全绒毛萎缩(III型)标本中的肥大细胞含量显著降低。

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