Kosnai I, Kuitunen P, Savilahti E, Sipponen P
J Pediatr Gastroenterol Nutr. 1984 Jun;3(3):368-72. doi: 10.1097/00005176-198406000-00011.
We counted the number of granulated mast cells with high iron diamine staining, and the number of eosinophils with hematoxyline-eosin staining, in the lamina propria of the jejunum in 12 untreated patients with intestinal cow's milk allergy (CMA), 47 with celiac disease (CD), and 14 controls. A decreased number of mast cells and an increased number of eosinophils were found in 58% of patients with CMA, and in 60% of those with CD. The number of mast cells showed a significant positive correlation with the villous height, and the number of eosinophils a negative correlation with both the villous height, and the number of mast cells. Appropriate dietary treatment resulted in a rise in the number of granulated mast cells and a decrease in the number of eosinophils in both patient groups.
我们对12例未经治疗的肠道牛奶过敏（CMA）患者、47例乳糜泻（CD）患者和14例对照者空肠固有层中高铁二胺染色的颗粒状肥大细胞数量以及苏木精-伊红染色的嗜酸性粒细胞数量进行了计数。在58%的CMA患者和60%的CD患者中发现肥大细胞数量减少而嗜酸性粒细胞数量增加。肥大细胞数量与绒毛高度呈显著正相关，嗜酸性粒细胞数量与绒毛高度及肥大细胞数量均呈负相关。适当的饮食治疗使两组患者的颗粒状肥大细胞数量增加，嗜酸性粒细胞数量减少。
