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[肠道吸收障碍综合征婴儿的空肠黏膜(超微结构与形态测量)]

[Jejunal mucosa in infants with the syndrome of disorders of intestinal absorption (ultrastructure and morphometry)].

作者信息

Kachko L Kh, Medne T A, Livshits E G, Novikova A V, Terent'eva L A

出版信息

Arkh Patol. 1978;40(2):45-51.

PMID:646663
Abstract

Ultrastructural studies and counts of interepithelial lymphocytes and the density of cellular infiltration of the lamina propria were carried out on 10 biopsies of the small intestine from infants of 4 months to 2 years with the syndrome of disturbed intestinal absorption. The greatest disorders were found to occur in celiac disease and intolerance to cow milk protein and to be manifested in subtotal atrophy of villi and destructive lesions of enterocytes. The authors believe that the marked infiltration of the epithelial layer with lymphocytes and the lamina propria of the mucous membrane with plasma cells represent manifestations of the local immunological response.

摘要

对4个月至2岁患有肠道吸收紊乱综合征的婴儿的10份小肠活检样本进行了超微结构研究,并对上皮间淋巴细胞进行了计数,同时测定了固有层的细胞浸润密度。结果发现,乳糜泻和对牛奶蛋白不耐受时出现的紊乱最为严重,表现为绒毛的部分萎缩和肠上皮细胞的破坏性病变。作者认为,上皮层淋巴细胞的显著浸润以及黏膜固有层浆细胞的浸润是局部免疫反应的表现。

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