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类风湿关节炎免疫抑制治疗期间酷似肺炎的肺梗死一例

A Case of Pulmonary Infarction Resembling Pneumonia during Immunosuppressive Treatment for Rheumatoid Arthritis.

作者信息

Kido Toshiki, Shinoda Koichiro, Tobe Kazuyuki

机构信息

First Department of Internal Medicine, University of Toyama, Toyama, Japan.

出版信息

Case Rep Rheumatol. 2021 Aug 18;2021:5983580. doi: 10.1155/2021/5983580. eCollection 2021.

Abstract

A 67-year-old woman with rheumatoid arthritis (RA) presented with fever and dyspnea. Chest radiography and computed tomography (CT) revealed pulmonary infiltrates with ground-glass opacities. We considered bacterial or pneumocystis pneumonia because she was immunocompromised due to RA treatment. However, she had tachycardia and elevated D-dimer levels. We performed contrast-enhanced CT and subsequently diagnosed her with pulmonary embolism (PE). Though PE is not usually accompanied by parenchymal pulmonary shadows, pulmonary infarction may cause pulmonary infiltrates that can be mistaken for pneumonia. As RA is a thrombophilic disease, clinicians should be aware of PE and pneumonia as differential diagnoses in such patients.

摘要

一名67岁的类风湿关节炎(RA)女性患者出现发热和呼吸困难。胸部X线和计算机断层扫描(CT)显示肺部有磨玻璃样混浊的浸润影。由于她因类风湿关节炎治疗而免疫功能低下,我们考虑为细菌性或肺孢子菌肺炎。然而,她有心动过速和D - 二聚体水平升高。我们进行了增强CT检查,随后诊断她为肺栓塞(PE)。虽然肺栓塞通常不伴有肺实质阴影,但肺梗死可能导致肺部浸润,可被误诊为肺炎。由于类风湿关节炎是一种易栓症疾病,临床医生应意识到在这类患者中肺栓塞和肺炎作为鉴别诊断的重要性。

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