Nguyen Thien, Khaksari Kosar, Khare Siddharth M, Park Soongho, Anderson Afrouz A, Bieda Janine, Jung Eunjung, Hsu Chaur-Dong, Romero Roberto, Gandjbakhche Amir H
National Institute of Child Health and Human Development, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20814, USA.
Department of Obstetrics and Gynecology, Wayne State University, 3990 John R. Street, Box 158, Detroit, MI 48201, USA.
Biomed Opt Express. 2021 Jun 15;12(7):4119-4130. doi: 10.1364/BOE.424969. eCollection 2021 Jul 1.
This study aimed to assess transabdominal placental oxygenation levels non-invasively. A wearable device was designed and tested in 12 pregnant women with an anterior placenta, 5 of whom had maternal pregnancy complications. Preliminary results revealed that the placental oxygenation level is closely related to pregnancy complications and placental pathology. Women with maternal pregnancy complications were found to have a lower placental oxygenation level (69.4% ± 6.7%) than those with uncomplicated pregnancy (75.0% ± 5.8%). This device is a step in the development of a point-of-care method designed to continuously monitor placental oxygenation and to assess maternal and fetal health.
本研究旨在无创评估经腹胎盘氧合水平。设计了一种可穿戴设备，并在12例前置胎盘孕妇中进行了测试，其中5例有母体妊娠并发症。初步结果显示，胎盘氧合水平与妊娠并发症及胎盘病理密切相关。发现有母体妊娠并发症的女性胎盘氧合水平（69.4%±6.7%）低于无并发症妊娠的女性（75.0%±5.8%）。该设备是开发一种即时护理方法的一个步骤，该方法旨在持续监测胎盘氧合并评估母婴健康。
