一名患有高危妊娠滋养细胞肿瘤的年轻女性的急性心肺衰竭：1例体外膜肺氧合支持下诱导化疗的病例
Acute cardiopulmonary failure in a young woman with high-risk gestational trophoblastic neoplasia: A case of induction chemotherapy during extracorporeal membrane oxygenation.
作者信息
McAlarnen Lindsey A, Smith Nathan J, Nance Beth A, Tracy Zundel M, Bishop Erin A
机构信息
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Department of Surgery, Division of Cardiothoracic Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.
出版信息
Gynecol Oncol Rep. 2021 Aug 14;37:100849. doi: 10.1016/j.gore.2021.100849. eCollection 2021 Aug.
•Early use of extracorporeal membrane oxygenation (ECMO) is valuable when pulmonary tumor burden from GTN is high.•Induction chemotherapy of cisplatin and etoposide was administered during ECMO successfully.•The induction chemotherapy regimen led to exponential decline in beta-HCG after 1 cycle.•Collaboration of subspecialists is necessary to treat coexisting malignancy and cardiopulmonary failure associated with GTN.
•当来自妊娠滋养细胞肿瘤（GTN）的肺部肿瘤负荷较高时，早期使用体外膜肺氧合（ECMO）很有价值。
•在ECMO期间成功给予顺铂和依托泊苷诱导化疗。
•诱导化疗方案在1个周期后导致β-人绒毛膜促性腺激素（β-HCG）呈指数下降。
•多学科专家合作对于治疗与GTN相关的并存恶性肿瘤和心肺衰竭是必要的。
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