己二酸哌嗪和丙硫咪唑对鸡蛔虫和鸡异刺线虫碳水化合物代谢的影响。
The effect of piperazine adipate and parbendazole on the carbohydrate metabolism of Ascaridia galli and Heterakis gallinae.
作者信息
Sharma R K, Singh K, Saxena K K
机构信息
Postgraduate Department of Zoology, Bareilly College, India.
出版信息
Angew Parasitol. 1987 Dec;28(4):207-10.
Carbohydrate metabolism of Ascardia galli and Heterakis gallinae was studied after their exposure in vitro to 10(-2) to 10(-5) M piperazine adipate and parbendazole for 10 to 60 min. Following treatment with 10(-2) M piperazine adipate O2 uptake was reduced by 87% in A. galli and 70% in H. gallinae, while parbendazole (10(-2) M) reduced O2 uptake by 70% and 86%, respectively. Glycogen contents were reduced significantly by 10(-2) M piperazine adipate in both the worms, while lactic acid level was enhanced. Parbendazole, however, did not cause any significant change in glycogen contents and lactic acid level in either parasite.
研究了鸡蛔虫（Ascardia galli）和鸡异刺线虫（Heterakis gallinae）在体外暴露于10⁻²至10⁻⁵ M己二酸哌嗪和丙硫咪唑10至60分钟后的碳水化合物代谢情况。用10⁻² M己二酸哌嗪处理后，鸡蛔虫的氧气摄取量减少了87%，鸡异刺线虫减少了70%，而丙硫咪唑（10⁻² M）分别使氧气摄取量减少了70%和86%。两种线虫体内的糖原含量均因10⁻² M己二酸哌嗪而显著降低，同时乳酸水平升高。然而，丙硫咪唑对两种寄生虫的糖原含量和乳酸水平均未引起任何显著变化。
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