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[流产、停止哺乳及维生素A暴露后大鼠乳腺的 involution(此处involution可能是退化、复旧等意思,需结合上下文准确理解)]

[Involution of rat mammae after abortion, cessation of lactation and vitamin A exposure].

作者信息

Nikitchenko V V, Andrushchak L A, Khaetskiĭ I K, Khaetskaia V I

出版信息

Arkh Anat Gistol Embriol. 1987 Nov;93(11):98-104.

PMID:3446103
Abstract

Structural changes in the mammary gland cells have been studied in rats electron microscopically during pregnancy and involution process after cessation of lactation, as well as at initiation processes by means of abortion at various time of pregnancy (on the 8th, 13th, 20th days). The involutional processes are demonstrated to depend on differentiation degree of the mammary gland cells: intensity of autolytic processes is essentially higher at abortion performed at late stages and at cessation of lactation. Stages of physiological death of the cells are followed. Vitamin A effect on the processes of differentiation and involution is investigated.

摘要

通过电子显微镜研究了大鼠在怀孕期、泌乳停止后的 involution 过程以及在怀孕不同时期(第8天、第13天、第20天)人工流产起始过程中乳腺细胞的结构变化。结果表明 involution 过程取决于乳腺细胞的分化程度:在晚期人工流产和泌乳停止时,自溶过程的强度明显更高。接着观察了细胞生理性死亡的阶段。研究了维生素A对分化和 involution 过程的影响。 (注:这里“ involution”在医学语境可能有“退化”“复旧”等意思,需结合更专业知识准确理解,但按要求未做额外解释)

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