University of Health Sciences Turkey Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey
Dokuz Eylül University Faculty of Medicine, Department of Ophthalmology, İzmir, Turkey
Turk J Ophthalmol. 2021 Aug 27;51(4):218-224. doi: 10.4274/tjo.galenos.2020.48376.
The effects of silicone endotamponade duration on the macula were evaluated in patients with rhegmatogenous retinal detachment.
Sixty-five eyes of 65 cases with rhegmatogenous retinal detachment that underwent pars plana vitrectomy and silicone endotamponade were included in the study. All cases were classified in three groups according to duration of silicone tamponade: ≤3 months, 3-6 months, and ≥6 months. All cases were evaluated at 1 week, 1 month, and 3 months after silicone injection, just before and at 1 month after silicone removal in terms of intraretinal pathologies in the macula by using spectral-domain optical coherence tomography (SD-OCT).
Sixteen (26.6%) of the patients were female and 49 (75.4%) were male. The mean age of the patients was 58.1±12.1 years (18-82); the mean follow-up time was 12.4±4 months (6-20). The mean duration of silicone tamponade was 6.7±2.3 months (2-12). In 26.6% of patients with ellipsoid zone/outer limiting membrane defect, a statistically significant improvement in reflectivity was detected after silicone oil removal (p=0.016). There was a significant increase in central foveal thickness after silicone removal in eyes with duration of silicone more than 3 months (p=0.003 for 3-6 months, p=0.006 for ≥6 months). The prevalence of cystoid macular edema before and after silicone removal was also significantly higher in the eyes with silicone duration of 6 months or longer (p<0.001).
In eyes with silicone endotamponade, structural changes in the macula may differ according to the duration of silicone oil in the eye.
评估硅油眼内填充时间对孔源性视网膜脱离患者黄斑的影响。
本研究纳入 65 例（65 只眼）行玻璃体切割联合硅油填充术的孔源性视网膜脱离患者。根据硅油填充时间将所有患者分为三组：≤3 个月、3-6 个月和≥6 个月。所有患者在硅油注入后 1 周、1 个月和 3 个月，以及硅油取出前和取出后 1 个月，均采用频域光相干断层扫描（SD-OCT）评估黄斑区视网膜内病变。
患者中女性 16 例（26.6%），男性 49 例（75.4%）；平均年龄 58.1±12.1 岁（18-82 岁）；平均随访时间 12.4±4 个月（6-20 个月）；硅油填充时间平均 6.7±2.3 个月（2-12 个月）。在 26.6%存在椭圆体带/外界膜缺损的患者中，硅油取出后反射率有统计学显著改善（p=0.016）。硅油填充时间超过 3 个月的患者，硅油取出后中央视网膜厚度显著增加（3-6 个月时 p=0.003，≥6 个月时 p=0.006）。硅油填充时间 6 个月或更长时间的患者，硅油取出前后黄斑囊样水肿的发生率也显著更高（p<0.001）。
在硅油眼内填充的眼中，黄斑区的结构变化可能因硅油在眼内的时间而有所不同。
