黄斑脱离视网膜脱离眼行玻璃体切除联合硅油与气体眼内填充术后视网膜内层变薄的比较
Thinning of Inner Retinal Layers after Vitrectomy with Silicone Oil versus Gas Endotamponade in Eyes with Macula-Off Retinal Detachment.
作者信息
Purtskhvanidze Konstantine, Hillenkamp Jost, Tode Jan, Junge Olaf, Hedderich Jürgen, Roider Johann, Treumer Felix
机构信息
Department of Ophthalmology, University Medical Center Schleswig-Holstein, Kiel, Germany.
出版信息
Ophthalmologica. 2017;238(3):124-132. doi: 10.1159/000477743. Epub 2017 Jul 19.
PURPOSE
To evaluate retinal layer thickness with optical coherence tomography (OCT) in eyes with macula-off retinal detachment after silicone oil (SiO) or gas endotamponade.
PROCEDURES
Cross-sectional study of 40 eyes with macula-off rhegmatogenous retinal detachment that underwent vitrectomy. 20 eyes received SiO tamponade and 20 matched eyes received gas. 33 healthy fellow eyes served as controls. Macular spectral domain OCT was performed with automated layer detection in the 5 inner subfields of the Early Treatment Diabetic Retinopathy Study (ETDRS) map.
RESULTS
Comparing the SiO group with the gas group, the ganglion cell layer showed a significant thinning in all fields of the inner ring of the ETDRS map, the inner plexiform layer in the nasal, superior and temporal quadrants, and the outer plexiform layer in the nasal quadrant.
CONCLUSIONS
Inner retinal layers in the fovea/parafovea were significantly thinner in the SiO group. Prospective studies are warranted to further elucidate possible retinal adverse effects of SiO tamponade.
目的
利用光学相干断层扫描（OCT）评估硅油（SiO）或气体眼内填充后黄斑脱离视网膜脱离眼的视网膜层厚度。
方法
对40例黄斑脱离孔源性视网膜脱离患者行玻璃体切除术进行横断面研究。20只眼接受SiO填充，20只配对眼接受气体填充。33只健康对侧眼作为对照。采用黄斑区光谱域OCT对糖尿病视网膜病变早期治疗研究（ETDRS）地图的5个内子区域进行自动分层检测。
结果
比较SiO组和气体组，神经节细胞层在ETDRS地图内环的所有区域均显著变薄，鼻侧、上方和颞侧象限的内丛状层以及鼻侧象限的外丛状层也显著变薄。
结论
SiO组中央凹/旁中央凹的视网膜内层明显变薄。有必要进行前瞻性研究以进一步阐明SiO填充可能对视网膜产生的不良影响。
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