Makanjuola R O, Adedapo S A
Department of Mental Health, University of Ife, Ife University Teaching Hospitals, Nigeria.
Br J Psychiatry. 1987 Nov;151:611-8. doi: 10.1192/bjp.151.5.611.
Consecutive new patients presenting at a Nigerian psychiatric unit over a 14-month period and fulfilling the DSM-III criteria for schizophreniform disorder, (active) schizophrenia and residual schizophrenia were studied. There were no differences between the three groups with respect to background social data. The schizophreniform patients had a lower incidence of previous psychotic episodes. There were no differences between the first two groups with respect to the distribution of PSE symptoms and signs, Schneider's First Rank Symptoms, or severity of psychopathology. Initial clinical outcome, and longer-term clinical and social outcome, assessed 25-38 months after index presentation, was best in the schizophreniform patients and worst in the patients with residual schizophrenia. The findings are consistent with schizophreniform disorder lying on a spectrum of schizophrenic disorders. They also highlight inadequacies in mental health services in Nigeria and other developing countries.
对在14个月期间前往尼日利亚一家精神科单位就诊的连续新患者进行了研究，这些患者符合精神分裂症样障碍、（活动期）精神分裂症和残留型精神分裂症的《精神疾病诊断与统计手册》第三版标准。三组患者在背景社会数据方面没有差异。精神分裂症样障碍患者既往精神病发作的发生率较低。前两组在PSE症状和体征分布、施奈德一级症状或精神病理学严重程度方面没有差异。在首次就诊后25 - 38个月评估的初始临床结局以及长期临床和社会结局，在精神分裂症样障碍患者中最佳，在残留型精神分裂症患者中最差。这些发现与精神分裂症样障碍处于精神分裂症谱系一致。它们还凸显了尼日利亚和其他发展中国家心理健康服务的不足。
