Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
School of Nursing Sciences, Tel Aviv Yaffo Academic College, Tel Aviv, Israel.
Anat Rec (Hoboken). 2022 May;305(5):1065-1072. doi: 10.1002/ar.24751. Epub 2021 Sep 4.
Previous studies have reported that osteophytes in the cervical vertebrae may cause immobility, neck stiffness, osteoarthritis, headaches, nerve entrapment syndromes, and compression of the vertebral artery. Our objective was to explore the osteophytes' expression on zygapophyseal joints C3-C7. This is a cross-sectional observational skeletal study. The study sample comprised 273 human skeletons of both sexes, aged 20-93, housed at the Natural History Museum, OH, USA. A grading system assessed the presence and severity of osteophytosis on the zygapophyseal joints. The chi-square test (SPSS 25.0) examined the association between osteophytes and demographic factors. The level of significance (α) was set at .05. The highest prevalence of osteophytes was found on C5 vertebra, the lowest on C7. On vertebrae C3, C4, C6, the rate of moderate and severe osteophytes found on the superior and inferior facets were comparable. Moderate and severe degrees of osteophytes were observed more frequently on the superior facets, whereas, on vertebra C7, osteophytes were found on the inferior facet joints. Osteophytes' prevalence was significantly higher in the elderly compared to the younger population. Osteophytes in the C3-C7 zygapophyseal joints are age-dependent. No significant sex and ethnic differences were observed. Vertebra C5 was most prone to develop osteophytes, most probably due to its location in the cervical lordotic peak, C5 in the superior ZF; C7 in the inferior ZF are significant (p = .05). The zygapophyseal joints of C7 were least frequent overall, yet, the C7 inferior facets had significantly more moderate-severe osteophytes compared to other cervical vertebrae.
先前的研究报告称，颈椎骨赘可能导致活动受限、颈部僵硬、骨关节炎、头痛、神经压迫综合征和椎动脉受压。我们的目的是探讨 C3-C7 椎间关节的骨赘表现。这是一项横断面观察性骨骼研究。研究样本包括美国俄亥俄州自然历史博物馆的 273 具男女骨骼，年龄在 20-93 岁之间。一个分级系统评估了椎间关节骨赘的存在和严重程度。卡方检验（SPSS 25.0）用于检验骨赘与人口统计学因素之间的关系。显著性水平（α）设定为.05。骨赘的最高发生率出现在 C5 椎体，最低出现在 C7 椎体。在 C3、C4、C6 椎体上，上下关节面中度和重度骨赘的发生率相当。在 C3、C4、C6 椎体上，上下关节面中度和重度骨赘更为常见，而在 C7 椎体上，骨赘出现在下关节面。与年轻人相比，老年人的骨赘患病率明显更高。C3-C7 椎间关节的骨赘与年龄有关。未观察到明显的性别和种族差异。C5 椎体最容易发生骨赘，这可能是由于其位于颈椎前凸顶点，C5 在上 ZF；C7 在 ZF 较低，有显著意义（p=0.05）。C7 椎间关节总体上发生频率最低，但 C7 下关节面的中度至重度骨赘明显多于其他颈椎。
