淋巴细胞性心肌炎，疑似合并肉芽肿性多血管炎，表现为心源性休克、限制性心肌病和完全性心脏传导阻滞。
Lymphocytic myocarditis with suspected granulomatosis with polyangiitis presenting as cardiogenic shock, restrictive cardiomyopathy and complete heart block.
作者信息
Anderson Wesley L, Bahrami Mubashir H, Guglin Maya, Rao Roopa
机构信息
Indiana University School of Medicine, Indianapolis, IN, USA.
出版信息
J Cardiol Cases. 2021 Feb 26;24(3):102-105. doi: 10.1016/j.jccase.2021.02.005. eCollection 2021 Sep.
We report a case of restrictive cardiomyopathy from lymphocytic myocarditis in a patient with suspected granulomatosis with polyangiitis (GPA). The case was complicated by complete heart block and renal failure. The diagnosis was supported by upper airway involvement, elevated serum serine proteinase 3 antibodies, and endomyocardial biopsy with lymphocytic infiltration. The patient responded appropriately to aggressive immunosuppressive therapy. < Our case reviews an atypical presentation of lymphocytic myocarditis and likely cardiac granulomatosis with polyangiitis (GPA). We also demonstrate an evaluation of restrictive physiology as well as discuss the presentations and management of cardiac GPA with its response to immunotherapy.>.
我们报告了一例疑似肉芽肿性多血管炎（GPA）患者因淋巴细胞性心肌炎导致的限制性心肌病。该病例并发完全性心脏传导阻滞和肾衰竭。上呼吸道受累、血清丝氨酸蛋白酶3抗体升高以及心内膜活检显示淋巴细胞浸润支持了诊断。患者对积极的免疫抑制治疗反应良好。<我们的病例回顾了淋巴细胞性心肌炎和可能的心脏肉芽肿性多血管炎（GPA）的非典型表现。我们还展示了对限制性生理学的评估，并讨论了心脏GPA的表现、管理及其对免疫治疗的反应。>
Zotero 插件