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枸杞根皮化学成分及药理研究进展

[Research progress on chemical constituents and pharmacological studies on root bark of Lycium barbarum].

作者信息

Chen Jing-Zhi, Lu Xing, Hu Yun-Qi, Guo Huan-Huan, Ma Xiao-Li, Guo Xin, Jiang Zhi-Bo, Wang Fang

机构信息

Key Laboratory of Chemical Engineering and Technology of State Ethnic Affairs Commission, School of Chemistry and Chemical Engineering, North Minzu University Yinchuan 750021, China.

Institute of Plant Protection, Ningxia Academy of Agriculture and Forestry Sciences Yinchuan 750002, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2021 Jun;46(12):3066-3075. doi: 10.19540/j.cnki.cjcmm.20210223.601.

DOI:10.19540/j.cnki.cjcmm.20210223.601
PMID:34467697
Abstract

Lycii Cortex, the dry root bark of Lycium barbarum(Solanaceae), is rich in chemical compositions with unique structures, such as organic acids, lipids, alkaloids, cyclopeptides and other components, and plays an important role in traditional Chinese medicine. It has the effect of cooling blood and removing steam, clearing lung and reducing fire. It is mainly used in the treatment of hot flashes due to Yin deficiency, hectic fever with night sweat, cough, hemoptysis and internal heat and diabetes. Modern pharmacological studies have shown that the crude extract or monomer of Lycii Cortex has a variety of pharmacological activities, such as hypoglycemic, hypotensive, hypolipidemic, antibacterial, and antiviral effects. In this paper, the chemical constituents and pharmacological effects of Cortex Lycii were reviewed in order to further clarify its effective substances, promote the development of medical undertakings, and ensure the "Healthy China" plan.

摘要

地骨皮为茄科植物枸杞的干燥根皮,富含具有独特结构的化学成分,如有机酸、脂类、生物碱、环肽等成分,在传统中药中发挥着重要作用。其具有凉血除蒸、清肺降火的功效。主要用于治疗阴虚潮热、盗汗、咳嗽、咯血及内热消渴等症。现代药理研究表明,地骨皮的粗提取物或单体具有多种药理活性,如降血糖、降血压、降血脂、抗菌及抗病毒作用。本文对地骨皮的化学成分及药理作用进行综述,以期进一步明确其有效物质,推动医药事业发展,保障“健康中国”计划。

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