Department of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia, USA.
Department of Neurosurgery, Emory University, Atlanta, Georgia, USA.
J Neuroimaging. 2022 Jan;32(1):57-62. doi: 10.1111/jon.12925. Epub 2021 Sep 1.
Percutaneous trigeminal tractotomy is an ablative procedure that can be used to treat trigeminal neuralgia in patients who have failed prior pharmacologic and surgical treatments. Using perioperative computed tomography (CT) guidance, ablation of the descending spinal trigeminal nucleus and trigeminal tract can be performed precisely to mitigate damage to surrounding structures. These patients are subsequently followed with postoperative imaging and clinical visits to assess long-term pain relief.
In this report, we present a series of four patients with trigeminal neuralgia who were had refractory disease after prior medical and surgical interventions. These patients underwent CT-guided percutaneous trigeminal tractotomy for pain relief. The patients underwent postoperative MRI and were followed for up to 6 months for long-term clinical outcomes.
For intraoperative CT, we find that preprocedure lumbar contrast injection enables better visualization of the cord during placement of the ablation probe. On postoperative imaging, we find that all four patients have hyperintense lesions on T2-weighted MRI that correspond with the location of the trigeminal nucleus and tract. Three patients had short-term pain relief, one of which continued to have long-term relief.
Intraoperative CT and postoperative MRI serve as useful modalities for confirming localization, evaluating complications, and can be used as a metric for quality control.
经皮三叉神经根切断术是一种消融性手术,可用于治疗先前药物和手术治疗失败的三叉神经痛患者。使用围手术期计算机断层扫描 (CT) 引导,可以精确地消融下降的脊三叉神经核和三叉神经束,以减轻对周围结构的损伤。这些患者随后进行术后影像学和临床随访,以评估长期疼痛缓解情况。
在本报告中,我们介绍了 4 例三叉神经痛患者,这些患者在先前的药物和手术干预后仍患有难治性疾病。这些患者接受了 CT 引导下的经皮三叉神经束切断术以缓解疼痛。患者接受了术后 MRI 检查,并随访了长达 6 个月以评估长期临床结果。
对于术中 CT,我们发现术前腰椎对比注射可在放置消融探针时更好地显示脊髓。在术后影像学上,我们发现所有 4 例患者的 T2 加权 MRI 上均有高信号病变,与三叉神经核和束的位置相对应。3 例患者有短期疼痛缓解,其中 1 例持续缓解。
术中 CT 和术后 MRI 是确认定位、评估并发症的有用方法,可作为质量控制的指标。