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视网膜内表面膜严重程度与脉络膜和视网膜中心厚度的术后病程。

The Postoperative Course of Choroidal and Central Retinal Thickness in Epiretinal Membranes with Respect to Membrane Severity.

机构信息

Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.

Vienna Clinical Trial Center, Medical University of Vienna, Vienna, Austria.

出版信息

Ophthalmic Res. 2021;64(6):1020-1028. doi: 10.1159/000519272. Epub 2021 Sep 1.

Abstract

INTRODUCTION

The aim of this study was to evaluate the relation between choroidal thickness (CT), central retinal thickness (CRT) and best-corrected visual acuity (BCVA) after surgery for idiopathic epiretinal membrane (iERM).

METHODS

Patients with 4 severity stages of iERM, who underwent vitrectomy with membrane- and internal limiting membrane peeling, were included in this prospective study. CRT, CT, and BCVA were assessed at baseline (BSL), 1 week, 1 and 3 months postoperatively.

RESULTS

Twenty-one eyes were phakic, 11 eyes pseudophakic at BSL, in 14 cases combined cataract surgery was performed. BCVA was highest in stage 1 and 2, lowest in stage 4 iERM (p < 0.001) and correlated with CRT. After surgery, CRT decreased and BCVA increased significantly (p < 0.05). CT did not show significant differences among stages (p = 0.23). BSL CRT did not differ between phakic and pseudophakic eyes, the least reduction after surgery was detected in patients who underwent combined cataract surgery and vitrectomy. BSL CT was greater in phakic than in pseudophakic eyes (p = 0.033). Postoperative CT decreased in pseudophakic and phakic eyes, but remained higher after combined surgery (p = 0.0048).

CONCLUSION

CT is not related to the severity of iERM. Choroidal changes did not influence the BCVA. Additional cataract surgery seems to cause longer recovery in CT and CRT.

摘要

介绍

本研究旨在评估特发性黄斑前膜(iERM)手术后脉络膜厚度(CT)、中心视网膜厚度(CRT)和最佳矫正视力(BCVA)之间的关系。

方法

本前瞻性研究纳入了 4 个严重程度分期的 iERM 患者,他们接受了玻璃体切除术联合内界膜和膜剥除术。在基线(BSL)、术后 1 周、1 个月和 3 个月评估 CRT、CT 和 BCVA。

结果

21 只眼为白内障眼,11 只眼为人工晶状体眼,14 例患者同时行白内障手术。BCVA 在 iERM 1 期和 2 期最高,4 期最低(p < 0.001),与 CRT 相关。手术后 CRT 显著降低,BCVA 显著升高(p < 0.05)。CT 在各分期之间无显著差异(p = 0.23)。BSL CRT 在白内障眼和人工晶状体眼中无差异,联合白内障手术和玻璃体切除术的患者术后 CRT 减少最少。BSL CT 在白内障眼中大于人工晶状体眼中(p = 0.033)。术后 CT 在人工晶状体眼和白内障眼中均降低,但联合手术后仍较高(p = 0.0048)。

结论

CT 与 iERM 的严重程度无关。脉络膜变化对 BCVA 没有影响。额外的白内障手术似乎会导致 CT 和 CRT 的恢复时间延长。

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