乳糜泻患者视网膜微血管灌注变化的评估
Evaluation of Retinal Microvascular Perfusion Changes in Patients with Celiac Disease.
作者信息
Erdem Seyfettin, Ucmak Feyzullah, Karahan Mine, Ava Sedat, Dursun Mehmet Emin, Dursun Birgul, Hazar Leyla, Yolaçan Ramazan, Keklikci Ugur
机构信息
Department Ophthalmology, Dicle University Medical Faculty, Diyarbakır, Turkey.
Department of Gastroenterology, Dicle University Medical Faculty, Diyarbakır, Turkey.
出版信息
Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):1876-1882. doi: 10.1080/09273948.2021.1968001. Epub 2021 Sep 3.
PURPOSE
We aimed to determine whether there are retinal microvascular changes in patients with celiac disease (CD).
METHODS
A total of 30 patients with CD (group 1) and 30 healthy controls (group 2) were included in this study. AngioVue optical coherence tomography angiography (OCTA) device was used to evaluate the retinal microvascular structure.
RESULTS
Some of the values of both optic nerve head (ONH) vessel density (VD) and radial peripapillary capillary VDs were found to be significantly lower in group 1 than in group 2. These 2 groups were similar except for one of the parameters of superficial capillary plexus VD (SCP-VD), whereas it was found that deep capillary plexus VD (DCP-VD) was lower in group 1 than in group 2 except for the foveal area.
CONCLUSION
It was determined that some VDs obtained from the ONH and DCP-VD obtained from most areas of the macular region were significantly lower.
目的
我们旨在确定乳糜泻（CD）患者是否存在视网膜微血管变化。
方法
本研究纳入了30例CD患者（第1组）和30名健康对照者（第2组）。使用AngioVue光学相干断层扫描血管造影（OCTA）设备评估视网膜微血管结构。
结果
发现第1组的视神经乳头（ONH）血管密度（VD）和放射状视乳头周围毛细血管VD的一些值显著低于第2组。除了浅表毛细血管丛VD（SCP-VD）的一个参数外，这两组在其他方面相似，而发现第1组的深层毛细血管丛VD（DCP-VD）在黄斑区除中央凹区域外均低于第2组。
结论
确定从ONH获得的一些VD以及从黄斑区大部分区域获得的DCP-VD显著降低。
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