Department of Surgical and Integrated Diagnostic Sciences, University of Genoa, Genoa, Italy.
Department of Clinical and Interventional Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Italy.
J Mech Behav Biomed Mater. 2021 Nov;123:104772. doi: 10.1016/j.jmbbm.2021.104772. Epub 2021 Aug 11.
Computational simulations of Transcatheter Aortic Valve Implantation (TAVI) have reached a high level of complexity and accuracy for the prediction of possible implantation scenarios during the decision-making process. However, when focusing on the prosthetic device, currently different devices are available on the market which not only have different geometries, but also different material properties. The present work focuses on the calibration of Nitinol constitutive parameters of four self-expandable devices starting from experimental radial force tests on the prosthetic samples. Beside providing optimal material properties for each specific device, we also perform a patient-specific simulation, comparing the results obtained using both "literature" and calibrated parameters with the aim of investigating the impact of metallic frame parameters choice on simulation results.
经导管主动脉瓣植入术（TAVI）的计算模拟在预测决策过程中可能的植入场景方面已经达到了高度的复杂性和准确性。然而，当关注假体装置时，目前市场上有不同的装置不仅具有不同的几何形状，而且具有不同的材料性能。本工作重点是从假体样本的径向力实验开始，对四个自扩张装置的 Nitinol 本构参数进行校准。除了为每个特定装置提供最佳的材料性能外，我们还进行了患者特定的模拟，比较使用“文献”和校准参数获得的结果，目的是研究金属框架参数选择对模拟结果的影响。
