Department of Experimental Medicine, University of Genova, Largo R. Benzi, 10, 16132 Genova, Italy.
Department of Electrical, Computer, and Biomedical Engineering, University of Pavia, Via Ferrata 5, 27100 Pavia, Italy.
Med Eng Phys. 2017 Sep;47:2-12. doi: 10.1016/j.medengphy.2017.06.045. Epub 2017 Jul 17.
In the last few years, several studies, each with different aim and modeling detail, have been proposed to investigate transcatheter aortic valve implantation (TAVI) with finite elements. The present work focuses on the patient-specific finite element modeling of the aortic valve complex. In particular, we aim at investigating how different modeling strategies in terms of material models/properties and discretization procedures can impact analysis results. Four different choices both for the mesh size (from 20 k elements to 200 k elements) and for the material model (from rigid to hyperelastic anisotropic) are considered. Different approaches for modeling calcifications are also taken into account. Post-operative CT data of the real implant are used as reference solution with the aim of outlining a trade-off between computational model complexity and reliability of the results.
在过去的几年中，已经提出了几项具有不同目的和建模细节的研究，旨在使用有限元方法研究经导管主动脉瓣植入术（TAVI）。本工作重点在于主动脉瓣复合体的患者特异性有限元建模。具体来说，我们旨在研究在材料模型/特性和离散化过程方面的不同建模策略如何影响分析结果。在网格大小（从 20k 个元素到 200k 个元素）和材料模型（从刚性到各向异性超弹性）方面都考虑了四种不同的选择。还考虑了用于模拟钙化的不同方法。将术后真实植入物的 CT 数据用作参考解决方案，旨在权衡计算模型的复杂性和结果的可靠性。
