Key Laboratory of Bio-Pesticide Innovation and Application of Guangdong Province, South China Agricultural University, Guangzhou 510642, China.
Department of Entomology, University of Kentucky, Lexington, KY 40546, USA; Research Center for Biomaterials, Indonesia Institute of Sciences, Jl. Raya Bogor km. 46, Cibinong, Bogor 16911, West Java, Indonesia.
Ecotoxicol Environ Saf. 2021 Dec 1;225:112743. doi: 10.1016/j.ecoenv.2021.112743. Epub 2021 Sep 1.
Fluralaner, a systemic pesticide, was originally registered with the US Food and Drug Administration in 2014 under the trade name Bravecto for flea treatment for pets. As a GABA antagonist, the footprint of fluralaner has expended beyond medical and veterinary pests in recent years. In this study, we examined the acute toxicity of fluralaner against three pests of Henosepilachna vigintioctopunctata, Megalurothrips usitatus, and Phyllotreta striolata in the Solanaceae, Fabaceae, and Cruciferae families, respectively, and the sublethal impact of fluralaner on Propylaea japonica, a widely distributed predatory ladybeetle. Based on LC, fluralaner was effective against H. vigintioctopunctata (0.098 mg a.i. L for the second instar larvae), M. usitatus (0.134 mg a.i. L for adult females), and P. striolata (0.595 mg a.i. L for adults). For P. japonica, however, fluralaner was substantially less effective (1.177 mg a.i. L for the third instar larvae). Furthermore, the LC and LC of P. japonica were also consistently higher than the LC of the three pests. In addition, we did not observe any significant impacts of fluralaner at LC and LC on the life history traits, including body weight, developmental time, pre-oviposition period, and fecundity of P. japonica. Based on our results from acute toxicities and sublethal impacts, fluralaner is effective against vegetable pests, while potentially friendly to P. japonica when employed as a biological control agent.
氟虫腈是一种系统性杀虫剂，最初于 2014 年以“Bravecto”的商品名在美国食品和药物管理局注册，用于宠物的跳蚤治疗。作为 GABA 拮抗剂，近年来氟虫腈的足迹已经超出了医学和兽医害虫。在这项研究中，我们检测了氟虫腈对茄科、豆科和十字花科三种害虫（二十八星瓢虫、烟盲蝽和黄曲条跳甲）的急性毒性，以及对广泛分布的捕食性瓢虫（龟纹瓢虫）的亚致死影响。基于 LC 值，氟虫腈对 H. vigintioctopunctata（二龄幼虫为 0.098mg a.i. L）、M. usitatus（雌性成虫为 0.134mg a.i. L）和 P. striolata（成虫为 0.595mg a.i. L）有效。然而，对于 P. japonica，氟虫腈的效果明显较差（三龄幼虫为 1.177mg a.i. L）。此外，P. japonica 的 LC 和 LC 值也始终高于三种害虫的 LC 值。此外，我们在 LC 和 LC 下没有观察到氟虫腈对龟纹瓢虫的生活史特征（包括体重、发育时间、产卵前期和繁殖力）有任何显著影响。根据我们的急性毒性和亚致死影响结果，氟虫腈对蔬菜害虫有效，而作为生物防治剂使用时对龟纹瓢虫可能具有友好性。
