Hsiao Wendy Chiawen, Abt Peter, Amaral Sandra, Levine Matthew, LaRosa Christopher
Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, USA.
Division of Transplant Surgery, Hospital of the University of Pennsylvania, Philadelphia, USA.
Pediatr Transplant. 2022 May;26(3):e14210. doi: 10.1111/petr.14210. Epub 2021 Dec 15.
Kidney allograft torsion is a rare complication of kidney transplant that can lead to allograft loss from prolonged ischemia if not quickly corrected with detorsion and nephropexy. We report a case of late intraperitoneal renal allograft torsion in a pediatric transplant recipient.
The patient is a 7-year-old male with a history of end-stage renal disease secondary to renal dysplasia in the setting of bilateral high-grade vesicoureteral reflux. He underwent bilateral native nephrectomies for recurrent pyelonephritis and right ureteral kink with urinary tract obstruction. Torsion occurred 3 years after transplant in the setting of one day of emesis, loose stool, severe abdominal pain, and decreased urine output. Diagnosis of transplant torsion was suspected on non-contrast CT scan done after transplant Doppler ultrasound showed no flow to the allograft. The CT scan showed that the kidney had been medialized and renal hilum was flipped from the expected orientation. The patient required a transplant nephrectomy.
Renal transplant torsion is a rare event but should be suspected in any renal transplant recipient with acute onset of abdominal pain, acute kidney injury, and decreased urine output, regardless of length of time from transplantation. Patients suspected to have renal torsion should be evaluated emergently with a transplant ultrasound Doppler.
肾移植扭转是肾移植的一种罕见并发症,如果不通过扭转复位和肾固定术迅速纠正,可因长时间缺血导致移植肾丢失。我们报告一例小儿肾移植受者发生的晚期腹膜内肾移植扭转病例。
该患者为一名7岁男性,有终末期肾病病史,病因是双侧重度膀胱输尿管反流伴肾发育不良。他因复发性肾盂肾炎和右侧输尿管扭结伴尿路梗阻接受了双侧自体肾切除术。移植后3年,在出现一天呕吐、腹泻、严重腹痛和尿量减少的情况下发生了扭转。移植后多普勒超声显示移植肾无血流,随后进行的非增强CT扫描怀疑移植肾扭转。CT扫描显示肾脏已向内侧移位,肾门从预期方向翻转。患者需要进行移植肾切除术。
肾移植扭转是一种罕见事件,但任何肾移植受者出现急性腹痛、急性肾损伤和尿量减少时,无论移植后时间长短,均应怀疑有此情况。怀疑有肾扭转的患者应紧急进行移植肾超声多普勒检查。