D'Hollander Curtis J, Keown-Stoneman Charles D G, Birken Catherine S, O'Connor Deborah L, Maguire Jonathon L
Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada; Department of Paediatrics, St Michael's Hospital, Toronto, Ontario, Canada; Applied Health Research Centre, Unity Health Toronto, Toronto, Ontario, Canada.
Applied Health Research Centre, Unity Health Toronto, Toronto, Ontario, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
J Pediatr. 2022 Jan;240:102-109.e3. doi: 10.1016/j.jpeds.2021.08.076. Epub 2021 Sep 2.
To evaluate the relationship between the timing of infant cereal introduction between 4 and 6 months of age and growth and dietary intake in later childhood.
A longitudinal cohort study was conducted among healthy children 0-10 years of age participating in The Applied Research Group for Kids cohort study between June 2008 and August 2019 in Toronto, Canada.
Of 8943 children included, the mean (SD) age of infant cereal introduction was 5.7 (2.1) months. In the primary analysis, children who were introduced to infant cereal at 4 vs 6 months had 0.17 greater body mass index z score (95% CI 0.06-0.28; P = .002) and greater odds of obesity (OR 1.82; 95% CI 1.18-2.80; P = .006) at 10 years of age. In the secondary analysis, children who were introduced to infant cereal at 4 vs 6 months had 0.09 greater height-for-age z score (95% CI 0.04-0.15; P = .002) at 1 year of age, an association that was not observed at 5 or 10 years of age. Children who were introduced to infant cereal at 4 vs 6 months had greater nutrition risk which was primarily determined by a less-favorable eating behavior score at 18 months to 5 years of age (0.18 units higher; 95% CI 0.07-0.29; P = .001).
Introduction of infant cereal at 4 vs 6 months was associated with greater body mass index z score, greater odds of obesity, similar height-for-age z score, and less favorable eating behavior. These findings support recommendations for introducing solid food around 6 months of age.
评估4至6个月龄婴儿开始食用谷物的时间与儿童后期生长及饮食摄入量之间的关系。
2008年6月至2019年8月在加拿大多伦多，对参与儿童应用研究组队列研究的0至10岁健康儿童进行了一项纵向队列研究。
纳入的8943名儿童中，开始食用婴儿谷物的平均（标准差）年龄为5.7（2.1）个月。在初步分析中，4个月与6个月开始食用婴儿谷物的儿童，10岁时体重指数z评分高0.17（95%置信区间0.06 - 0.28；P = 0.002），肥胖几率更高（比值比1.82；95%置信区间1.18 - 2.80；P = 0.006）。在二次分析中，4个月与6个月开始食用婴儿谷物的儿童，1岁时年龄别身高z评分高0.09（95%置信区间0.04 - 0.15；P = 0.002），5岁或10岁时未观察到这种关联。4个月与6个月开始食用婴儿谷物的儿童营养风险更高，这主要由18个月至5岁时较差的饮食行为评分决定（高0.18分；95%置信区间0.07 - 0.29；P = 0.001）。
4个月与6个月开始食用婴儿谷物与更高的体重指数z评分、更高的肥胖几率、相似的年龄别身高z评分以及较差的饮食行为有关。这些发现支持在6个月左右开始添加固体食物的建议。
