Boulder, Colorado.
Prog Biophys Mol Biol. 2021 Oct;165:153-156. doi: 10.1016/j.pbiomolbio.2021.08.009. Epub 2021 Sep 3.
A recent symposium on cancer and evolution has bought many innovative thinkers together to challenge the status quo of current cancer research. Professor Henry Heng's presentation considers cancer as a new system emerging via macro-evolution, where genome chaos-mediated information creation and maintenance plays an important role. This concept departs from the neo-Darwinian influenced somatic mutation theory of cancer. To appreciate his theory, it is helpful to briefly review several of his heterodox findings in the fields of oncology and evolutionary biology. This letter summarizes and highlights these findings and calls for a medical and scientific reckoning as well as integration within and between these fields.
最近一次关于癌症与进化的研讨会聚集了许多创新思想家，共同挑战当前癌症研究的现状。亨瑞·恒教授的演讲认为癌症是一种通过宏观进化而出现的新系统，其中基因组混沌介导的信息创造和维持起着重要作用。这一概念背离了受新达尔文主义影响的癌症体细胞突变理论。为了理解他的理论，简要回顾一下他在肿瘤学和进化生物学领域的一些非正统发现会有所帮助。这封信总结并强调了这些发现，并呼吁在这些领域内部和之间进行医学和科学的反思和整合。
