特发性帕金森病患者的精神疾病发病率：一项横断面研究。
Psychiatric morbidity in patients with idiopathic Parkinson's disease: A cross-sectional study.
作者信息
Kumar Santhosh, Avasthi Ajit, Modi Manish, Grover Sandeep
机构信息
Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Ind Psychiatry J. 2021 Jan-Jun;30(1):165-174. doi: 10.4103/ipj.ipj_8_21. Epub 2021 Jun 24.
OBJECTIVE
To evaluate the prevalence of psychiatric comorbidities in patients with idiopathic Parkinson's disease (IPD).
METHODOLOGY
Two hundred and thirty-nine patients with IPD were evaluated on Mini-International Neuropsychiatric Interview PLUS (MINI-PLUS). In addition, patients found to have depression as per the MINI-PLUS were evaluated on Beck Depression Inventory.
RESULTS
One hundred and thirty-five (56.5%) patients had a current psychiatric diagnosis and 59.8% had a lifetime psychiatric diagnosis. As per MINI-PLUS, about two-fifth (39.7%) of patients had suicidality. In 18.8% of patients, suicidality was present in the absence of axis-I psychiatric diagnosis. Among the various psychiatric disorders, the most common disorders included depressive disorders (current: 17.5%; lifetime: 23.8%), anxiety disorders (current: 17.5%; lifetime: 17.5%), and psychotic disorders (current: 11.3%; lifetime: 11.7%).
CONCLUSIONS
More than half of the patients with Parkinson's disease have psychiatric disorders. High prevalence of psychiatric morbidity calls for close liaison between the neurologist and the psychiatric disorders.
目的
评估特发性帕金森病（IPD）患者中精神疾病共病的患病率。
方法
采用迷你国际神经精神访谈升级版（MINI-PLUS）对239例IPD患者进行评估。此外，根据MINI-PLUS发现有抑郁症的患者，用贝克抑郁量表进行评估。
结果
135例（56.5%）患者目前有精神疾病诊断，59.8%患者曾有精神疾病诊断。根据MINI-PLUS，约五分之二（39.7%）的患者有自杀倾向。18.8%的患者在没有轴I精神疾病诊断的情况下存在自杀倾向。在各种精神疾病中，最常见的疾病包括抑郁症（目前：17.5%；曾患：23.8%）、焦虑症（目前：17.5%；曾患：17.5%）和精神障碍（目前：11.3%；曾患：11.7%）。
结论
超过一半的帕金森病患者患有精神疾病。精神疾病的高患病率要求神经科医生和精神科医生密切联系。
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